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Plans Required to Cover Treatment for SOD1-ALS ARLINGTON, Va. , Dec. 11, 2024 /PRNewswire/ -- The Centers for Medicare & Medicaid Services (CMS) has announced a first-of-its-kind directive requiring Medicare Advantage plans to approve coverage for Qalsody, a treatment for people living with genetic SOD1-ALS. This decision reflects the ALS Association's commitment to ensuring that people living with ALS have access to promising ALS treatments without delay. "This is a victory for the entire ALS community," said Calaneet Balas, president and CEO of the ALS Association. "It's critical that FDA-approved treatments are made accessible rather than being labeled as 'experimental.' We are grateful to everyone in our community who helped make this day happen." Balas added: "We hope this sends a message to the entire rare disease community and pharmaceutical industry that new treatments can be developed and made accessible to those who will benefit from them. We need to ensure more ALS treatments are developed and approved that will help everyone living with ALS." The ALS Association played a key role in the historic CMS directive by participating and advocating for the research, approval, and accessibility of Qalsody for people living with ALS. In 2004, the ALS Association was the first to fund research into ALS-specific antisense oligonucleotide (ASO) technology, investing over $1.3 million in groundbreaking studies that laid the foundation for the development of Qalsody. This early commitment supported preclinical studies, safety trials, and the first-in-human phase 1 trial, which established SOD1 as a viable therapeutic target. In 2023, Qalsody became the first gene-based therapy approved for ALS , thanks in part to the ALS Association's efforts, including a united push from the ALS community for FDA accelerated approval. This new CMS directive provides precedent for state regulators to issue similar actions for other private insurers. According to the Valor study published in 2022 , Qalsody, which was developed specifically to target the RNA produced by mutated SOD1 genes, has demonstrated significant promise in clinical trials and real-world studies. In the phase 3 VALOR trial, Qalsody reduced levels of mutated SOD1 proteins in cerebral spinal fluid by 35% within eight weeks and decreased bloodstream levels of neurofilament light chain (NfL)—a key biomarker of neurodegeneration—by 50% within 12-16 weeks. These biological changes translated into measurable clinical benefits, including slower disease progression, improved respiratory function, and enhanced quality of life after 52 weeks of treatment. Real-world data has since validated these findings, with some patients stabilizing or even experiencing improvements in motor function and quality of life. When insurance companies began denying access to Qalsody, labeling it as "experimental," the ALS Association took decisive action, working directly with CMS to launch an investigation into these unjust denials. By presenting evidence of widespread insurance rejections and demonstrating the critical need for immediate intervention. In addition to working with CMS, the ALS Association actively engaged policymakers, held strategic meetings with state and federal legislators, and served as a staunch advocate for patients, ensuring their voices were heard and their rights to life-changing treatment were upheld. The ALS Association urges anyone previously denied Qalsody by their Medicare Advantage plan to contact their ALS specialist immediately to begin the process of securing access to this critical treatment. For more information on the CMS directive visit als.org About the ALS Association The ALS Association is the largest ALS organization in the world. The ALS Association funds global research collaborations, assists people with ALS and their families through its nationwide network of care and certified clinical care centers, and advocates for better public policies for people with ALS. The ALS Association is working to make ALS a livable disease while urgently searching for new treatments and a cure. For more information about the ALS Association, visit our website at www.als.org . About ALS Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease that affects nerve cells in the brain and spinal cord. Over the course of the disease, people lose the ability to move, to speak, and eventually, to breathe. The disease is always fatal, usually within five years of diagnosis. Few treatment options exist, resulting in a high unmet need for new therapies to address functional deficits and disease progression. View original content to download multimedia: https://www.prnewswire.com/news-releases/groundbreaking-directive-ensures-als-patients-on-medicare-advantage-gain-access-to-qalsody-302329525.html SOURCE The ALS Associationare koi fish illegal in california 。

BUENOS AIRES (AP) — Thiago Messi, the eldest son of the Argentina star, has made his debut in the “Newell’s Cup” tournament in the countryside city of Rosario. The 12-year-old Messi played with the No. 10 jersey of an Inter Miami youth team, which lost 1-0 on Monday to host Newell’s Old Boys in the traditional under-13 competition. The team also played Tuesday. Lionel Messi took his first steps as a footballer in the Argentinian club in Rosario, 300 kilometers (186 miles) northwest of capital Buenos Aires. Thiago's mother, Antonela Roccuzzo, and several members of his family, including grandparents Jorge Messi and Celia Cuccittini, were in the stands to watch him play. Lionel Messi did not attend. Thiago, who was substituted in the second half, played with his friend Benjamín Suárez, son of Uruguayan striker Luis Suárez, Messi's teammate and close friend at Barcelona and now at Inter Miami. Messi and Suárez are in Rosario after Inter Miami’s early elimination in the MLS playoffs. On Sunday, they watched a friendly game of Inter Miami's U13 team against Unión at the same sports complex. The youth tournament in Argentina brings together eight teams from North and South America. AP soccer: https://apnews.com/hub/soccerNike has always had a foot grounded in history and the other soaring towards the future. The Air Foamposite Pro , while unorthodox and dismissed upon first release, would go on to revolutionize the sneaker game since it debuted in 1997. The “Pearl” iteration, which launched not long after the coveted “Dark Neon Royal” colorway, is being re-released next year as part of the Swoosh’s holiday 2025 drop. Roughly eight years since the last “Pearl” retro, the much anticipated model is rumored to stay true to the OG, sporting a lustrous cream upper made of a synthetic molded polyurethane that is both durable and lightweight. Details include contrasting black nubuck accents and mesh inner lining, as well as Nike branding along the base, toebox and heel. While the Air Foamposite Pro isn’t tied to a star athlete, it equally gained pop cultural resonance through Spike Lee’s 1998 film, He Got Game , where the shoes were seen donned by Jesus Shuttleworth, played by NBA Hall of Famer Ray Allen. The forthcoming Air Foamposite Pro “Pearl” will release on Nike and select stores in roughly a year.The hardest movie ticket to get this weekend was for a film audiences have been able to watch at home for years: Christopher Nolan’s “Interstellar.” The science fiction epic starring Matthew McConaughey and Anne Hathaway earned $4.5 million from only 166 screens in the U.S. and Canada. Its 70mm IMAX film presentations sold out in minutes, leaving theaters scrambling to add more and people paying up to $300 on the re-sale market. Those 10 film screens alone had a staggering $70,000 per theater average, one of the highest of the year and usually the bragging rights of acclaimed arthouse movies playing on only four screens. Ten years after “Interstellar” was given a film release as a special exception at time when its studio, Paramount, was committing to a digital future, film is not only back but driving audiences to theaters. “I was just so gratified by the response,” Nolan said in an exclusive interview with The Associated Press. “It’s really thrilling when people respond to your work at any point. But 10 years later, to have new audiences coming and experiencing it in the way that we’d originally intended it on the big IMAX screens and in particular on those IMAX film prints? It’s really rewarding to see that it continues to have a life.” “Interstellar” had been a labor of love, with Nolan fighting against the tides of a changing industry to use film, certain of its value. Like McConaughey’s Cooper, an astronaut clinging to skills that were all but obsolete in his dust bowl reality, “Interstellar” was made by a celluloid-loving filmmaker when the format was least valued. “Celluloid film was very threatened. Digital was taking over everything,” Nolan said. “We put an enormous amount of work and effort into the IMAX 70mm film format release at the time feeling like we didn’t know how much longer we’d be able to do that.” During its time, “Interstellar” was received warmly and an unambiguous success, but it also had its detractors. Its five Oscar nominations and win were all for crafts. And yet in the decade since, “Interstellar” has become beloved, a true classic. Nolan observed that it was the film that people kept wanting to talk about, telling him what it meant to them and asking if it was ever going to be re-released. Those grand emotions and sentimental themes of love, family and exploration that were a liability with some are now its most cherished qualities. “A lot of these people were younger people who, it was clear to me, had seen the film in the home and hadn’t had the chance to see it on the big screen,” Nolan said. While there have been “Interstellar” rereleases internationally, in China and at the Science Museum in London, Nolan saw an opportunity and spoke to IMAX and Paramount, now under a new regime, about a proper North American re-release for its 10th anniversary. The prints, Nolan said, hadn't aged a day. IMAX hardly needed convincing: They’ve had the anniversary date circled on the calendar. For years, “Interstellar” was by far the biggest request on their social channels. “We saw this coming from the beginning,” IMAX CEO Rich Gelfond said. “It reminded us in a small way of the frenzy around ‘Oppenheimer.’ But the result is far beyond our expectations." “Interstellar” is now the ninth highest-grossing IMAX release of all time and is closing in on eight (currently occupied by “The Last Jedi.”) The company is currently exploring options for re-releases in different territories. The “Oppenheimer" effect was real in redeeming film's value for the business. IMAX screens accounted for some 20% of the nearly $1 billion this year's Oscar best picture winner made globally (it ranks at No. 5 for IMAX). While filmmakers have long cherished film stock, “Oppenheimer” had studios, distributors and theaters taking note of the demand. Earlier this year the film showings of “Dune: Part Two” were sold out for four weeks. And there's more to come: Ryan Coogler's new film “Sinners," opening in March 2025, was shot with IMAX cameras. The “Interstellar” release was fairly “low key" when it came to promotion, but it also didn’t need much — fans made sure of that. Before IMAX had even announced that tickets were on sale, some noticed that AMC had made them available. News spread on socials and overnight every 70mm IMAX showing at the Lincoln Square location in New York had sold out. It wasn’t just the “primetime” slots either: The 1 AM showtimes were at capacity too. After the weekend's turnout surpassed expectations, they added more 70mm IMAX screenings through the week which also filled up quickly. While Nolan is in some ways an anomaly, as the rare filmmaker whose name alone can draw crowds for original fare, there are lessons to be learned from the weekend. “It just shows our industry once again that audiences truly understand the difference between a communal, big screen theatrical experience that they crave even on films that they’ve had the opportunities to see in the home,” Nolan said. “That theatrical experience that we all know and love is so powerful and so exciting. It’s a very clear demonstration of it, especially coming amidst all the great successes right now, “Wicked,”“Gladiator II,”“Moana 2.” "Audiences are coming out in droves for that experience that we all love so much.” Before the weekend, Nolan was able to see the film again on the big screen for the first time since the original release, accompanied by his Oscar-winning “Oppenheimer” cinematographer Hoyte van Hoytema. “Interstellar” was their first collaboration and Hoytema’s introduction to IMAX cameras (where he proved that they could be handheld if you tried hard enough). “It was really, really fun," Nolan said. He also approved the new 4K UHD “Interstellar" set that's now available. Since “Oppenheimer's" big night at the Oscars and Nolan's best director win, there's been much speculation about his next film with near daily rumors circulating about casting and genre, none of which have been officially confirmed. It's not something he's speaking publicly about yet. One thing he will say, however, is that he’s in the throes of intensive testing for a new film technology with IMAX to use in the next production. “They have an incredible engineering staff, really brilliant minds doing extraordinary work,” he said. “It’s wonderful to see innovation in the celluloid film arena still happening and happening at the highest level possible.” And he’s still making time to go to the movies Over the weekend, Nolan went to see “Wicked” at a theater in Burbank where he also peeked into one of the IMAX presentations of his film. “It was pretty magical to see a full house on that film,” he said. “It was a very special thing to see, 10 years later.”

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MANILA, Philippines – PHINMA Corporation raised P1-billion in a stock rights offering (SRO) conducted in November. From November 13 to 19, the company sold 50 million shares for P20 each. The shares were listed at the Philippine Stock Exchange on Wednesday, November 27. “PHINMA shall continue to serve Filipino families and communities by providing the essentials to a dignified life through the unified efforts of our businesses and investments in industries enabling us to make an even bigger impact on our society and country,” PHINMA Chairman and Chief Executive Officer Ramon del Rosario Jr. said. “We look forward to your continued support as we pursue our lofty business goals and longstanding commitment to making lives better,” he added. At least P250 million of the proceeds will be spent to construct PHINMA Hospitality’s TRYP by Wyndham hotel within the group’s 21-hectare Saludad township in Bacolod City. Without mentioning specifics, the company said P239.56 million will be for investments in socialized housing, food security, healthcare, the green industry, and for general corporate purposes. “Thanks to the continued support of our shareholders, we are proactively strengthening our balance sheet while maintaining the flexibility to make strategic investments that will fuel our future success,” PHINMA Chief Financial Officer EJ Qua Hiansen said. A big chunk of the SRO proceeds will also finance the company’s facility expansion for its units. The SRO will fund the construction of a P210-million facillity in Pampanga that will have a yearly capacity of one million square meters for Union Insulated Panel Corporation, the company’s unit that produces insulation panels . Meanwhile, Philcement Corporation is allocated P114 million for the construction of its modern cement manufacturing facility in in Davao del Norte, which the company said will produce about two million metric tons a year. The company also plans on spending P200 million for PHINMA Properties projects in Bacolod, Cebu, and Davao. Meanwhile, PHINMA Solar Energy Corporation will get P170 million to cover for the 58 government projects it was able to get through the Green Energy Auction Program. – Rappler.comTexas A&M signed the nation’s top-ranked recruiting class three years ago believing it had built a potential national title contender. Plenty of players from that heralded 2022 class could indeed be participating in the first 12-team College Football Playoff this month. They just won’t be doing it for the Aggies, who no longer have nearly half their 2022 signees. The list of 2022 recruits now with playoff contenders elsewhere includes Mississippi defensive lineman Walter Nolen, Oregon wide receiver Evan Stewart, Alabama defensive lineman LT Overton, SMU offensive tackle PJ Williams and injured Boise State receiver Chris Marshall. Texas A&M has done all right without them, going 8-4 as transfers filled about half the starting roles. Texas A&M represents perhaps the clearest example of how recruiting and roster construction have changed in the era of loosened transfer restrictions. Coaches must assemble high school classes without always knowing which of their own players are transferring and what players from other schools could be available through the portal. “It used to be you lost 20 seniors, you signed 20 incoming freshmen,” Duke coach Manny Diaz said. “You just had your numbers right. Now you might lose 20 seniors, but you might lose 20 underclassmen. You just don’t know.” Coaches emphasize that high school recruiting remains critical, but recent results suggest it isn’t as vital as before. The last two College Football Playoff runners-up – TCU in 2022 and Washington in 2023 – didn’t sign a single top-15 class in any of the four years leading up their postseason runs, according to composite rankings of recruiting sites compiled by 247Sports. This year’s contenders have shown there’s more than one way to build a championship-caliber roster. About half of No. 1 Oregon’s usual starters began their college careers elsewhere. No. 5 Georgia, which annually signs one of the nation’s top high school classes, has only a few transfers making major contributions. Colorado’s rise under Deion Sanders exemplifies how a team can win without elite high school recruiting. None of Colorado’s last four classes have ranked higher than 30th in the 247Sports Composite. Three ranked 47th or lower. “If anybody ever did the homework and the statistics of these young men – people have a class that they say is the No. 1 class in the nation – then five of those guys play, or four of those guys play, then the rest go through the spring and then they jump in the portal,” Sanders said. “Don’t give me the number of where you rank (in recruiting standings), because it’s like an NFL team," he added. "You always say who won the draft, then the team gets killed all year (and) you don’t say nothing else about it. Who won the draft last year in the NFL? Nobody cares right now, right?” Wisconsin's Christian Alliegro tries to stop Oregon's Evan Stewart, right, during the first half of a Nov. 16 game in Madison, Wis. Star quarterback Shedeur Sanders followed his father from Jackson State to Colorado in 2023, and Heisman Trophy front-runner Travis Hunter accompanied them. According to Colorado, this year’s Buffaloes team has 50 transfer newcomers, trailing only North Texas’ 54 among Bowl Subdivision programs. Relying on transfers comes with caveats. Consider Florida State's rise and fall. Florida State posted an unbeaten regular-season record last year with transfers playing leading roles. When those transfers departed and Florida State's portal additions this year didn't work out, the Seminoles went 2-10. “There has to be some type of balance between the transfer portal and high school recruiting,” said Andrew Ivins, the director of scouting for 247Sports. “I compare it to the NFL. The players from the transfer portal are your free agents and high school recruiting is your NFL draft picks.” A look at the composite rankings of recruiting sites compiled by 247Sports for the 2020-22 classes shows at least 40 of the top 100 prospects each of those years ended up leaving their original school. Coaches must decide which positions they’re better off building with high school prospects and which spots might be easier to fill through the portal. “The ones that have a ton of learning to do - tight end, quarterback, interior offensive line, inside linebacker, safety, where they are the communicators - they are the guys that are processing a lot of information,” Florida’s Billy Napier said. “Those are the ones in a perfect world you have around for a while. “It’s easier to play defensive line, edge, corner, receiver, running back, tackle, specialists. Those are a little bit more plug-and-play I’d say, in my opinion," Napier said. "Either way, it’s not necessarily about that. It’s just about we need a certain number at each spot, and we do the best we can to fill those roles.” Colorado head coach Deion Sanders, right, congratulates place kicker Cristiano Palazzo after he kicked an extra point during the second half of Friday's game against Oklahoma Stat in Boulder, Colo. Power Four programs aren’t the only ones facing a balancing act between recruiting high schools and mining the transfer portal. Group of Five schools encounter similar challenges. “We’re recruiting every position and bringing in a high school class,” Eastern Michigan coach Chris Creighton said. “That’s not going to be maybe 24 scholarship guys like it used to be. It might be more like 16. It’s not four d-linemen necessarily, right? It might be three. It might not be three receivers. It might be two. And it might not be five offensive linemen. It’s two to three.” The extra hurdle Group of Five schools face is the possibility their top performers might leave for a power-conference program with more lucrative name, image and likeness financial opportunities. They sometimes don’t know which players they’ll lose. “We know who they’re trying to steal,” Miami (Ohio) coach Chuck Martin quipped. “We just don’t know who they’re going to steal.” The obstacles facing coaches are only getting steeper as FBS teams prepare for a 105-man roster limit as part of the fallout from a pending $2.8 billion NCAA antitrust settlement. While having 105 players on scholarship seems like an upgrade from the current 85-man scholarship limit, many rosters have about 125 players once walk-ons are included. Nebraska coach Matt Rhule said last week his program would probably end up with about 30-50 players in the portal due to the new roster restrictions. All the added dimensions to roster construction in the college game have drawn parallels to the NFL, but Minnesota coach P.J. Fleck believes those comparisons are misleading. “When people talk about college football right now, they’re saying, ‘Oh, we have an NFL model,’ or it’s kind of moving toward the NFL,” Fleck said. “First of all, it’s nothing like the NFL. There’s a collective bargaining agreement (in the NFL). There’s a true salary cap for everybody. It’s designed for all 32 fan bases to win the Super Bowl maybe once every 32 years – and I know other people are winning that a lot more than others – but that’s how it’s designed. In college football, it’s not that way.” There does seem to be a bit more competitive balance than before. The emergence of TCU and Washington the last couple of postseasons indicates this new era of college football has produced more unpredictability. Yet it’s also created many more challenges as coaches try to figure out how to put together their rosters. “It’s difficult because we’re just kind of inventing it on the fly, right?” Diaz said. Buffalo Bills quarterback Josh Allen, foreground right, dives toward the end zone to score past San Francisco 49ers defensive end Robert Beal Jr. (51) and linebacker Dee Winters during the second half of an NFL football game in Orchard Park, N.Y., Sunday, Dec. 1, 2024. (AP Photo/Adrian Kraus) Houston Rockets guard Jalen Green goes up for a dunk during the second half of an Emirates NBA cup basketball game against the Minnesota Timberwolves, Tuesday, Nov. 26, 2024, in Minneapolis. (AP Photo/Abbie Parr) Mari Fukada of Japan falls as she competes in the women's Snowboard Big Air qualifying round during the FIS Snowboard & Freeski World Cup 2024 at the Shougang Park in Beijing, Saturday, Nov. 30, 2024. (AP Photo/Andy Wong) LSU punter Peyton Todd (38) kneels in prayer before an NCAA college football game against Oklahoma in Baton Rouge, La., Saturday, Nov. 30, 2024. LSU won 37-17. (AP Photo/Gerald Herbert) South Africa's captain Temba Bavuma misses a catch during the fourth day of the first Test cricket match between South Africa and Sri Lanka, at Kingsmead stadium in Durban, South Africa, Saturday, Nov. 30, 2024. (AP Photo/Themba Hadebe) Los Angeles Kings left wing Warren Foegele, left, trips San Jose Sharks center Macklin Celebrini, center, during the third period of an NHL hockey game Monday, Nov. 25, 2024, in San Jose, Calif. (AP Photo/Godofredo A. Vásquez) Olympiacos' Francisco Ortega, right, challenges for the ball with FCSB's David Miculescu during the Europa League league phase soccer match between FCSB and Olympiacos at the National Arena stadium, in Bucharest, Romania, Thursday, Nov. 28, 2024. (AP Photo/Andreea Alexandru) Brazil's Botafogo soccer fans react during the Copa Libertadores title match against Atletico Mineiro in Argentina, during a watch party at Nilton Santos Stadium, in Rio de Janeiro, Saturday, Nov. 30, 2024. (AP Photo/Bruna Prado) Seattle Kraken fans react after a goal by center Matty Beniers against the San Jose Sharks was disallowed due to goaltender interference during the third period of an NHL hockey game Saturday, Nov. 30, 2024, in Seattle. The Sharks won 4-2. (AP Photo/Lindsey Wasson) New York Islanders left wing Anders Lee (27), center, fight for the puck with Boston Bruins defensemen Parker Wotherspoon (29), left, and Brandon Carlo (25), right during the second period of an NHL hockey game, Wednesday, Nov. 27, 2024, in Elmont, N.Y. (AP Photo/Julia Demaree Nikhinson) Jiyai Shin of Korea watches her shot on the 10th hole during the final round of the Australian Open golf championship at the Kingston Heath Golf Club in Melbourne, Australia, Sunday, Dec. 1, 2024. (AP Photo/Asanka Brendon Ratnayake) Lara Gut-Behrami, of Switzerland, competes during a women's World Cup giant slalom skiing race, Saturday, Nov. 30, 2024, in Killington, Vt. (AP Photo/Robert F. Bukaty) New York Islanders goaltender Ilya Sorokin cools off during first period of an NHL hockey game against the Boston Bruins, Wednesday, Nov. 27, 2024, in Elmont, N.Y. (AP Photo/Julia Demaree Nikhinson) Brazil's Amanda Gutierres, second right, is congratulated by teammate Yasmin, right, after scoring her team's first goal during a soccer international between Brazil and Australia in Brisbane, Australia, Thursday, Nov. 28, 2024. (AP Photo/Pat Hoelscher) Las Vegas Raiders tight end Brock Bowers (89) tries to leap over Kansas City Chiefs cornerback Joshua Williams (2) during the first half of an NFL football game in Kansas City, Mo., Friday, Nov. 29, 2024. (AP Photo/Ed Zurga) Gold medalists Team Netherlands competes in the Team Sprint Women race of the ISU World Cup Speed Skating Beijing 2024 held at the National Speed Skating Oval in Beijing, Sunday, Dec. 1, 2024. (AP Photo/Ng Han Guan) Minnesota Vikings running back Aaron Jones (33) reaches for an incomplete pass ahead of Arizona Cardinals linebacker Mack Wilson Sr. (2) during the second half of an NFL football game Sunday, Dec. 1, 2024, in Minneapolis. (AP Photo/Abbie Parr) Melanie Meillard, center, of Switzerland, competes during the second run in a women's World Cup slalom skiing race, Sunday, Dec. 1, 2024, in Killington, Vt. (AP Photo/Robert F. Bukaty) South Carolina guard Maddy McDaniel (1) drives to the basket against UCLA forward Janiah Barker (0) and center Lauren Betts (51) during the first half of an NCAA college basketball game, Sunday, Nov. 24, 2024, in Los Angeles. (AP Photo/Eric Thayer) Philadelphia Eagles running back Saquon Barkley, left, is hit by Baltimore Ravens cornerback Marlon Humphrey, center, as Eagles wide receiver Parris Campbell (80) looks on during a touchdown run by Barkley in the second half of an NFL football game, Sunday, Dec. 1, 2024, in Baltimore. (AP Photo/Stephanie Scarbrough) Mathilde Gremaud of Switzerland competes in the women's Freeski Big Air qualifying round during the FIS Snowboard & Freeski World Cup 2024 at the Shougang Park in Beijing, Friday, Nov. 29, 2024. (AP Photo/Andy Wong) Luiz Henrique of Brazil's Botafogo, right. is fouled by goalkeeper Everson of Brazil's Atletico Mineiro inside the penalty area during a Copa Libertadores final soccer match at Monumental stadium in Buenos Aires, Argentina, Saturday, Nov. 30, 2024. (AP Photo/Natacha Pisarenko) England's Alessia Russo, left, and United States' Naomi Girma challenge for the ball during the International friendly women soccer match between England and United States at Wembley stadium in London, Saturday, Nov. 30, 2024. (AP Photo/Kirsty Wigglesworth) Get local news delivered to your inbox!BEIRUT: Israel and Lebanese armed group Hezbollah are set to implement a ceasefire on Wednesday (Nov 27) as part of a United States-proposed deal for a 60-day truce to end more than a year of hostilities. The text of the deal has not been published and Reuters has not seen a draft. Israel's security cabinet has approved the deal and it will be put to the whole cabinet for review. Lebanon and Hezbollah have agreed to the proposal and the Lebanese cabinet will meet on Wednesday to formalise its approval. The deal, negotiated by US mediator Amos Hochstein, is five pages long and includes 13 sections, according to a senior Lebanese political source with direct knowledge of the deal. Here is a summary of its key provisions. HALT TO HOSTILITIES The halt to hostilities is set to begin 12 hours after an anticipated announcement on Tuesday night, with both sides expected to cease fire by Wednesday morning, two senior Lebanese political sources with direct knowledge of the deal said. One of them said Israel was expected to "stop carrying out any military operations against Lebanese territory, including against civilian and military targets, and Lebanese state institutions, through land, sea and air". All armed groups in Lebanon - meaning Hezbollah and its allies - would halt operations against Israel, the source said. ISRAELI TROOPS WITHDRAW Two Israeli officials said the Israeli military would withdraw from southern Lebanon within 60 days. Lebanon had earlier pushed for Israeli troops to withdraw as quickly as possible within the truce period, Lebanese officials told Reuters. They now expect Israeli troops to withdraw within the first month, the senior Lebanese political source said. HEZBOLLAH PULLS NORTH, LEBANESE ARMY DEPLOYS Hezbollah fighters will leave their positions in southern Lebanon to move north of the Litani River, which runs about 30km north of the border with Israel. Their withdrawal will not be public, the senior Lebanese political source said. He said the group's military facilities "will be dismantled" but it was not immediately clear whether the group would take them apart itself, or whether the fighters would take their weapons with them as they withdrew. The Lebanese army would deploy troops to south of the Litani to have around 5,000 soldiers there, including at 33 posts along the border with Israel, a Lebanese security source told Reuters. "The deployment is the first challenge - then how to deal with the locals that want to return home", given the risks of unexploded ordnance, the source said. More than 1.2 million people have been displaced by Israeli strikes in Lebanon, many of them from south Lebanon. Hezbollah sees the return of the displaced to their homes as a priority, Hezbollah lawmaker Hassan Fadlallah told Reuters. Tens of thousands displaced from northern Israel are also expected to return home. MONITORING MECHANISM One of the sticking points in the final days leading to the ceasefire's conclusion was how it would be monitored, Lebanon's deputy speaker of parliament Elias Bou Saab told Reuters. A pre-existing tripartite mechanism between the United Nations peacekeeping force in southern Lebanon (UNIFIL), the Lebanese army and the Israeli army would be expanded to include the US and France, with the US chairing the group, Bou Saab said. Israel would be expected to flag possible breaches to the monitoring mechanism, and France and the US together would determine whether a violation had taken place, an Israeli official and a Western diplomat told Reuters. UNILATERAL ISRAELI STRIKES Israeli officials have insisted that the Israeli army would continue to strike Hezbollah if it identified threats to its security, including transfers of weapons and military equipment to the group. An Israeli official told Reuters that US envoy Amos Hochstein, who negotiated the agreement, had given assurances directly to Israeli Prime Minister Benjamin Netanyahu that Israel could carry out such strikes on Lebanon. Netanyahu said in a televised address after the security cabinet met that Israel would strike Hezbollah if it violated the deal. The official said Israel would use drones to monitor movements on the ground in Lebanon. Lebanese officials say that provision is not in the deal that it agreed, and that it would oppose any violations of its sovereignty.

Portland Trail Blazers @ Los Angeles Clippers Current Records: Portland 8-13, Los Angeles 13-9 When: Tuesday, December 3, 2024 at 10:30 p.m. ET Where: Intuit Dome -- Inglewood, California TV: FanDuel SN - SoCal Follow: CBS Sports App Online Streaming: Catch select NBA matches on Fubo (Try for free. Regional restrictions may apply.) Ticket Cost: $25.00 The Trail Blazers are 1-9 against the Clippers since November of 2021 but they'll have a chance to close the gap a little bit on Tuesday. The Portland Trail Blazers will head out to face off against the Los Angeles Clippers at 10:30 p.m. ET at Intuit Dome. The Trail Blazers have been getting the ball to fall more lately as they've increased their point totals each of their last three games. The Trail Blazers are headed in fresh off scoring the most points they have all season. They took a 137-131 hit to the loss column at the hands of the Mavericks. Having run the score up that high, both teams might be doing some extra defensive drills very soon. Anfernee Simons put forth a good effort for the losing side as he went 6 for 8 from beyond the arc en route to 27 points plus five assists. The dominant performance also gave him a new career-high in field goal percentage (81.8%). Even though they lost, the Trail Blazers were working as a unit and finished the game with 29 assists. That strong performance was nothing new for the team: they've now posted at least 27 assists in three consecutive games. Meanwhile, there's no place like home for the Clippers, who bounced back after a tough loss on the road on Friday. They snuck past the Nuggets with a 126-122 victory on Sunday. The score was all tied up 59-59 at the break, but Los Angeles was the better team in the second half. James Harden had an outrageously good game as he almost dropped a triple-double on 39 points, nine rebounds, and 11 assists. Another player making a difference was Norman Powell, who posted 28 points. Portland's loss ended a four-game streak of wins at home and dropped them to 8-13. As for Los Angeles, they pushed their record up to 13-9 with the win, which was their eighth straight at home. The Trail Blazers are hoping to beat the odds on Tuesday, as the experts think they're headed for a loss. This contest will be their 15th straight as the underdogs (so far over this stretch they are 8-6 against the spread). The Trail Blazers barely slipped by the Clippers in their previous meeting back in October, winning 106-105. Do the Trail Blazers have another victory up their sleeve, or will the Clippers turn the tables on them? We'll have the answer soon enough. Los Angeles is a big 8.5-point favorite against Portland, according to the latest NBA odds . Bettors have moved against the Clippers slightly, as the game opened with the Clippers as a 10.5-point favorite. The over/under is 218 points. See NBA picks for every single game, including this one, from SportsLine's advanced computer model. Get picks now . Los Angeles has won 9 out of their last 10 games against Portland. Oct 30, 2024 - Portland 106 vs. Los Angeles 105 Mar 22, 2024 - Los Angeles 125 vs. Portland 117 Mar 20, 2024 - Los Angeles 116 vs. Portland 103 Dec 11, 2023 - Los Angeles 132 vs. Portland 127 Oct 25, 2023 - Los Angeles 123 vs. Portland 111 Apr 08, 2023 - Los Angeles 136 vs. Portland 125 Mar 19, 2023 - Los Angeles 117 vs. Portland 102 Nov 29, 2022 - Los Angeles 118 vs. Portland 112 Dec 06, 2021 - Los Angeles 102 vs. Portland 90 Nov 09, 2021 - Los Angeles 117 vs. Portland 109