Jimmy Carter: Many evolutions for a centenarian ‘citizen of the world’Homan taking death threats against him ‘more seriously’ after Trump officials targeted with violent threats
Drama surrounds final three F1 races of seasonGrizzlies’ Vince Williams Jr. to miss at least four weeks with ankle sprainBe careful what you wish for
100 percent of evaluable patients for minimal residual disease (MRD) testing achieved MRD negativity in MajesTEC-5 as induction therapy and MajesTEC-4 as maintenance therapy SAN DIEGO , Dec. 8, 2024 /PRNewswire/ -- Johnson & Johnson (NYSE:JNJ) today announced new frontline data featuring TECVAYLI ® (teclistamab-cqyv) from two investigational studies in patients with newly diagnosed multiple myeloma (NDMM) in induction and maintenance settings. The MajesTEC-5 ( Abstract #493 ) and MajesTEC-4 ( Abstract #494 ) studies establish the potential of TECVAYLI ® for use in newly diagnosed patients, with promising efficacy and a tolerable safety profile. These data were highlighted as oral presentations at the 2024 American Society of Hematology (ASH) Annual Meeting. 1,2 Forty-nine patients with transplant-eligible NDMM were treated with TECVAYLI ® in combination with DARZALEX FASPRO ® (daratumumab and hyaluronidase-fihj), lenalidomide and dexamethasone (Tec-DRd) or DARZALEX FASPRO ® , bortezomib, lenalidomide and dexamethasone (Tec-DVRd) as induction therapy in the MajesTEC-5 study. 1 All patients who were evaluated for MRD negativity after cycle 3 of induction therapy achieved MRD negativity (10 -5 ) and maintained through cycle 6. 1 "These data from the MajesTEC-5 study build on the growing body of evidence of TECVAYLI combinations that support the potential combinability of TECVAYLI with other effective therapies, demonstrating high rates of MRD-negative responses for evaluable patients with newly diagnosed multiple myeloma," said Rachel Kobos, M.D., Vice President, Oncology Research & Development, Johnson & Johnson Innovative Medicine. "At Johnson & Johnson, our deep expertise and understanding of multiple myeloma has shaped the regimens we're developing, including our bispecific antibodies in new combinations, and we're committed to exploring the full potential of our therapies to improve outcomes for patients." The safety profiles were manageable and consistent with individual safety profiles. 1 No treatment-emergent adverse events (TEAEs) led to study treatment discontinuation or death; cytokine release syndrome (CRS; Grade 1 or 2) occurred in 65 percent of patients. 1 No patients experienced immune effector cell-associated neurotoxicity syndrome (ICANS). 1 Grade 3/4 TEAEs included lymphopenia (43 percent), neutropenia (57 percent) and infections (35 percent). 1 "There remains opportunity to achieve even deeper and more sustained outcomes for a broader patient population in the frontline setting," said Marc S. Raab , M.D., Heidelberg University Hospital, Germany .* "These data reinforce the potential of TECVAYLI when used in earlier lines and show that TECVAYLI can be leveraged to optimize existing standard regimens in combination." Results from the safety run-in of the Phase 3 MajesTEC-4 study highlighted the potential of TECVAYLI ® to be administered as a maintenance therapy following autologous stem cell transplant (ASCT). 2 MajesTEC-4 is the first study to present data on a B-cell maturation antigen (BCMA) bispecific as monotherapy or combination therapy after ASCT. 2 Low rates of non-hematologic Grade 3/4 TEAEs and discontinuation of treatment due to all TEAEs (5.3 percent) were observed. CRS events were all Grade 1/2, mostly occurring during step-up dosing, and ICANS was not observed. Neutropenia and infections were the most common Grade 3/4 TEAEs. 2 Grade 3/4 neutropenia at 6 months showed a decreased trend in cohorts 2 and 3 with less frequent TECVAYLI ® dosing (cohort 1: 94 percent, cohort 2: 63 percent, cohort 3: 47 percent). 2 A similar trend was observed for all-grade infections (cohort 1: 94 percent; cohort 2: 78 percent; cohort 3: 77 percent). 2 All evaluable patients in cohort 1 who underwent MRD assessment after 12 months of therapy were MRD negative, and 100 percent of evaluable patients assessed in cohorts 2 and 3 were also MRD negative at cycle 6. 2 Further analysis of combination therapies will be evaluated in the Phase 3 MajesTEC-7 study, which is currently enrolling. About MajesTEC-5 Study MajesTEC-5 ( NCT05695508 ) is an ongoing, Phase 2 study of teclistamab and talquetamab, evaluating the safety and efficacy of combination regimens in participants with newly diagnosed transplant eligible multiple myeloma. 3 About MajesTEC-4 Study MajesTEC-4 ( NCT05243797 ) is an ongoing, multicenter, randomized, open-label, Phase 3 study of teclistamab in combination with lenalidomide and teclistamab alone versus lenalidomide alone in participants with newly diagnosed multiple myeloma as maintenance therapy following autologous stem cell transplantation. 4 About MajesTEC-7 Study MajesTEC-7 ( NCT05552222 ) is a Phase 3 randomized study comparing teclistamab in combination with daratumumab SC and lenalidomide (Tec-DR) and talquetamab in combination with daratumumab SC and lenalidomide (Tal-DR) versus daratumumab SC, lenalidomide, and dexamethasone (DRd) in participants with newly diagnosed multiple myeloma who are either ineligible or not intended for autologous stem cell transplant as initial therapy. 5 About TECVAYLI ® TECVAYLI ® (teclistamab-cqyv) received approval from the U.S. FDA in October 2022 as an off-the-shelf (or ready-to-use) antibody that is administered as a subcutaneous treatment for adult patients with relapsed or refractory multiple myeloma (RRMM) who have received at least four prior lines of therapy, including a proteasome inhibitor, an immunomodulatory agent and an anti-CD38 antibody. 6 The European Commission (EC) granted TECVAYLI ® conditional marketing authorization (CMA) in August 2022 as monotherapy for the treatment of adult patients with RRMM who have received at least three prior therapies, including a proteasome inhibitor, an immunomodulatory agent and an anti-CD38 antibody, and have demonstrated disease progression since the last therapy. In August 2023 , the EC granted the approval of a Type II variation application for TECVAYLI ® , providing the option for a reduced dosing frequency of 1.5 mg/kg every two weeks in patients who have achieved a complete response (CR) or better for a minimum of six months. TECVAYLI ® is a first-in-class, bispecific T-cell engager antibody therapy that uses innovative science to activate the immune system by binding to the CD3 receptor expressed on the surface of T-cells and to the B-cell maturation antigen (BCMA) expressed on the surface of multiple myeloma cells and some healthy B-lineage cells. In February 2024 , the U.S. FDA approved the supplemental Biologics License Application (sBLA) for TECVAYLI ® for a reduced dosing frequency of 1.5 mg/kg every two weeks (Q2W) in patients with relapsed or refractory multiple myeloma who have achieved and maintained a CR or better for a minimum of six months. For more information, visit www.TECVAYLI.com . About DARZALEX FASPRO ® and DARZALEX ® DARZALEX FASPRO ® (daratumumab and hyaluronidase-fihj) received U.S. FDA approval in May 2020 and is approved for nine indications in multiple myeloma, four of which are for frontline treatment in newly diagnosed patients who are transplant eligible or ineligible. It is the only subcutaneous CD38-directed antibody approved to treat patients with MM. DARZALEX FASPRO ® is co-formulated with recombinant human hyaluronidase PH20, Halozyme's ENHANZE ® drug delivery technology. DARZALEX ® is the first CD38-directed antibody approved to treat multiple myeloma. DARZALEX ® -based regimens have been used in the treatment of more than 585,000 patients worldwide and more than 239,000 patients in the U.S. alone. In August 2012 , Janssen Biotech, Inc. and Genmab A/S entered a worldwide agreement, which granted Janssen an exclusive license to develop, manufacture and commercialize daratumumab. For more information, visit https://www.darzalexhcp.com. About Multiple Myeloma Multiple myeloma is an incurable blood cancer that affects a type of white blood cell called plasma cells, which are found in the bone marrow. 7 In multiple myeloma, these plasma cells proliferate and spread rapidly and replace normal cells in the bone marrow with tumors. 8 Multiple myeloma is the third most common blood cancer worldwide and remains an incurable disease. 9 In 2024, it was estimated that more than 35,000 people will be diagnosed with multiple myeloma in the U.S. and more than 12,000 people would die from the disease. 10 People living with multiple myeloma have a 5-year survival rate of 59.8 percent. 11 While some people diagnosed with multiple myeloma initially have no symptoms, most patients are diagnosed due to symptoms that can include bone fracture or pain, low red blood cell counts, tiredness, high calcium levels and kidney problems or infections. 12,13 TECVAYLI ® IMPORTANT SAFETY INFORMATION WARNING: CYTOKINE RELEASE SYNDROME and NEUROLOGIC TOXICITY including IMMUNE EFFECTOR CELL- ASSOCIATED NEUROTOXICITY SYNDROME Cytokine release syndrome (CRS), including life-threatening or fatal reactions, can occur in patients receiving TECVAYLI ® . Initiate treatment with TECVAYLI ® step-up dosing schedule to reduce risk of CRS. Withhold TECVAYLI ® until CRS resolves or permanently discontinue based on severity. Neurologic toxicity, including Immune Effector Cell-Associated Neurotoxicity Syndrome (ICANS) and serious and life- threatening reactions, can occur in patients receiving TECVAYLI ® . Monitor patients for signs or symptoms of neurologic toxicity, including ICANS, during treatment. Withhold TECVAYLI ® until neurologic toxicity resolves or permanently discontinue based on severity. TECVAYLI ® is available only through a restricted program called the TECVAYLI ® and TALVEY ® Risk Evaluation and Mitigation Strategy (REMS). INDICATION AND USAGE TECVAYLI ® (teclistamab-cqyv) is a bispecific B-cell maturation antigen (BCMA)-directed CD3 T-cell engager indicated for the treatment of adult patients with relapsed or refractory multiple myeloma who have received at least four prior lines of therapy, including a proteasome inhibitor, an immunomodulatory agent and an anti-CD38 monoclonal antibody. This indication is approved under accelerated approval based on response rate. Continued approval for this indication may be contingent upon verification and description of clinical benefit in confirmatory trial(s). WARNINGS AND PRECAUTIONS Cytokine Release Syndrome - TECVAYLI ® can cause cytokine release syndrome (CRS), including life-threatening or fatal reactions. In the clinical trial, CRS occurred in 72% of patients who received TECVAYLI ® at the recommended dose, with Grade 1 CRS occurring in 50% of patients, Grade 2 in 21%, and Grade 3 in 0.6%. Recurrent CRS occurred in 33% of patients. Most patients experienced CRS following step-up dose 1 (42%), step-up dose 2 (35%), or the initial treatment dose (24%). Less than 3% of patients developed first occurrence of CRS following subsequent doses of TECVAYLI ® . The median time to onset of CRS was 2 (range: 1 to 6) days after the most recent dose with a median duration of 2 (range: 1 to 9) days. Clinical signs and symptoms of CRS included, but were not limited to, fever, hypoxia, chills, hypotension, sinus tachycardia, headache, and elevated liver enzymes (aspartate aminotransferase and alanine aminotransferase elevation). Initiate therapy according to TECVAYLI ® step-up dosing schedule to reduce risk of CRS. Administer pretreatment medications to reduce risk of CRS and monitor patients following administration of TECVAYLI ® accordingly. At the first sign of CRS, immediately evaluate patient for hospitalization. Administer supportive care based on severity and consider further management per current practice guidelines. Withhold or permanently discontinue TECVAYLI ® based on severity. TECVAYLI ® is available only through a restricted program under a REMS. Neurologic Toxicity including ICANS - TECVAYLI ® can cause serious or life-threatening neurologic toxicity, including Immune Effector Cell-Associated Neurotoxicity Syndrome (ICANS). In the clinical trial, neurologic toxicity occurred in 57% of patients who received TECVAYLI ® at the recommended dose, with Grade 3 or 4 neurologic toxicity occurring in 2.4% of patients. The most frequent neurologic toxicities were headache (25%), motor dysfunction (16%), sensory neuropathy (15%), and encephalopathy (13%). With longer follow-up, Grade 4 seizure and fatal Guillain-Barré syndrome (one patient each) occurred in patients who received TECVAYLI ® . In the clinical trial, ICANS was reported in 6% of patients who received TECVAYLI ® at the recommended dose. Recurrent ICANS occurred in 1.8% of patients. Most patients experienced ICANS following step-up dose 1 (1.2%), step-up dose 2 (0.6%), or the initial treatment dose (1.8%). Less than 3% of patients developed first occurrence of ICANS following subsequent doses of TECVAYLI ® . The median time to onset of ICANS was 4 (range: 2 to 8) days after the most recent dose with a median duration of 3 (range: 1 to 20) days. The most frequent clinical manifestations of ICANS reported were confusional state and dysgraphia. The onset of ICANS can be concurrent with CRS, following resolution of CRS, or in the absence of CRS. Monitor patients for signs and symptoms of neurologic toxicity during treatment. At the first sign of neurologic toxicity, including ICANS, immediately evaluate patient and provide supportive therapy based on severity. Withhold or permanently discontinue TECVAYLI ® based on severity per recommendations and consider further management per current practice guidelines. Due to the potential for neurologic toxicity, patients are at risk of depressed level of consciousness. Advise patients to refrain from driving or operating heavy or potentially dangerous machinery during and for 48 hours after completion of TECVAYLI ® step-up dosing schedule and in the event of new onset of any neurologic toxicity symptoms until neurologic toxicity resolves. TECVAYLI ® is available only through a restricted program under a REMS. TECVAYLI ® and TALVEY ® REMS - TECVAYLI ® is available only through a restricted program under a REMS called the TECVAYLI ® and TALVEY ® REMS because of the risks of CRS and neurologic toxicity, including ICANS. Hepatotoxicity - TECVAYLI ® can cause hepatotoxicity, including fatalities. In patients who received TECVAYLI ® at the recommended dose in the clinical trial, there was one fatal case of hepatic failure. Elevated aspartate aminotransferase (AST) occurred in 34% of patients, with Grade 3 or 4 elevations in 1.2%. Elevated alanine aminotransferase (ALT) occurred in 28% of patients, with Grade 3 or 4 elevations in 1.8%. Elevated total bilirubin occurred in 6% of patients with Grade 3 or 4 elevations in 0.6%. Liver enzyme elevation can occur with or without concurrent CRS. Monitor liver enzymes and bilirubin at baseline and during treatment as clinically indicated. Withhold TECVAYLI ® or consider permanent discontinuation of TECVAYLI ® based on severity. Infections - TECVAYLI ® can cause severe, life-threatening, or fatal infections. In patients who received TECVAYLI ® at the recommended dose in the clinical trial, serious infections, including opportunistic infections, occurred in 30% of patients, with Grade 3 or 4 infections in 35%, and fatal infections in 4.2%. Monitor patients for signs and symptoms of infection prior to and during treatment with TECVAYLI ® and treat appropriately. Administer prophylactic antimicrobials according to guidelines. Withhold TECVAYLI ® or consider permanent discontinuation of TECVAYLI ® based on severity. Monitor immunoglobulin levels during treatment with TECVAYLI ® and treat according to guidelines, including infection precautions and antibiotic or antiviral prophylaxis. Neutropenia - TECVAYLI ® can cause neutropenia and febrile neutropenia. In patients who received TECVAYLI ® at the recommended dose in the clinical trial, decreased neutrophils occurred in 84% of patients, with Grade 3 or 4 decreased neutrophils in 56%. Febrile neutropenia occurred in 3% of patients. Monitor complete blood cell counts at baseline and periodically during treatment and provide supportive care per local institutional guidelines. Monitor patients with neutropenia for signs of infection. Withhold TECVAYLI ® based on severity. Hypersensitivity and Other Administration Reactions - TECVAYLI ® can cause both systemic administration-related and local injection-site reactions. Systemic Reactions - In patients who received TECVAYLI ® at the recommended dose in the clinical trial, 1.2% of patients experienced systemic-administration reactions, which included Grade 1 recurrent pyrexia and Grade 1 swollen tongue. Local Reactions - In patients who received TECVAYLI ® at the recommended dose in the clinical trial, injection-site reactions occurred in 35% of patients, with Grade 1 injection-site reactions in 30% and Grade 2 in 4.8%. Withhold TECVAYLI ® or consider permanent discontinuation of TECVAYLI ® based on severity. Embryo-Fetal Toxicity - Based on its mechanism of action, TECVAYLI ® may cause fetal harm when administered to a pregnant woman. Advise pregnant women of the potential risk to the fetus. Advise females of reproductive potential to use effective contraception during treatment with TECVAYLI ® and for 5 months after the last dose. ADVERSE REACTIONS The most common adverse reactions (≥20%) were pyrexia, CRS, musculoskeletal pain, injection site reaction, fatigue, upper respiratory tract infection, nausea, headache, pneumonia, and diarrhea. The most common Grade 3 to 4 laboratory abnormalities (≥20%) were decreased lymphocytes, decreased neutrophils, decreased white blood cells, decreased hemoglobin, and decreased platelets. Please read full Prescribing Information , including Boxed WARNING, for TECVAYLI ® . DARZALEX FASPRO ® INDICATIONS AND IMPORTANT SAFETY INFORMATION INDICATIONS DARZALEX FASPRO ® (daratumumab and hyaluronidase-fihj) is indicated for the treatment of adult patients with multiple myeloma: IMPORTANT SAFETY INFORMATION CONTRAINDICATIONS DARZALEX FASPRO ® is contraindicated in patients with a history of severe hypersensitivity to daratumumab, hyaluronidase, or any of the components of the formulation. WARNINGS AND PRECAUTIONS Hypersensitivity and Other Administration Reactions Both systemic administration-related reactions, including severe or life-threatening reactions, and local injection-site reactions can occur with DARZALEX FASPRO ® . Fatal reactions have been reported with daratumumab-containing products, including DARZALEX FASPRO ® . Systemic Reactions In a pooled safety population of 1249 patients with multiple myeloma (N=1056) or light chain (AL) amyloidosis (N=193) who received DARZALEX FASPRO ® as monotherapy or in combination, 7% of patients experienced a systemic administration-related reaction (Grade 2: 3.2%, Grade 3: 0.7%, Grade 4: 0.1%). Systemic administration-related reactions occurred in 7% of patients with the first injection, 0.2% with the second injection, and cumulatively 1% with subsequent injections. The median time to onset was 2.9 hours (range: 5 minutes to 3.5 days). Of the 165 systemic administration-related reactions that occurred in 93 patients, 144 (87%) occurred on the day of DARZALEX FASPRO ® administration. Delayed systemic administration-related reactions have occurred in 1% of the patients. Severe reactions included hypoxia, dyspnea, hypertension, tachycardia, and ocular adverse reactions, including choroidal effusion, acute myopia, and acute angle closure glaucoma. Other signs and symptoms of systemic administration-related reactions may include respiratory symptoms, such as bronchospasm, nasal congestion, cough, throat irritation, allergic rhinitis, and wheezing, as well as anaphylactic reaction, pyrexia, chest pain, pruritus, chills, vomiting, nausea, hypotension, and blurred vision. Pre-medicate patients with histamine-1 receptor antagonist, acetaminophen, and corticosteroids. Monitor patients for systemic administration-related reactions, especially following the first and second injections. For anaphylactic reaction or life-threatening (Grade 4) administration-related reactions, immediately and permanently discontinue DARZALEX FASPRO ® . Consider administering corticosteroids and other medications after the administration of DARZALEX FASPRO ® depending on dosing regimen and medical history to minimize the risk of delayed (defined as occurring the day after administration) systemic administration-related reactions. Ocular adverse reactions, including acute myopia and narrowing of the anterior chamber angle due to ciliochoroidal effusions with potential for increased intraocular pressure or glaucoma, have occurred with daratumumab-containing products. If ocular symptoms occur, interrupt DARZALEX FASPRO ® and seek immediate ophthalmologic evaluation prior to restarting DARZALEX FASPRO ® . Local Reactions In this pooled safety population, injection-site reactions occurred in 7% of patients, including Grade 2 reactions in 0.8%. The most frequent (>1%) injection-site reaction was injection-site erythema. These local reactions occurred a median of 5 minutes (range: 0 minutes to 6.5 days) after starting administration of DARZALEX FASPRO ® . Monitor for local reactions and consider symptomatic management. Neutropenia Daratumumab may increase neutropenia induced by background therapy. Monitor complete blood cell counts periodically during treatment according to manufacturer's prescribing information for background therapies. Monitor patients with neutropenia for signs of infection. Consider withholding DARZALEX FASPRO ® until recovery of neutrophils. In lower body weight patients receiving DARZALEX FASPRO ® , higher rates of Grade 3-4 neutropenia were observed. Thrombocytopenia Daratumumab may increase thrombocytopenia induced by background therapy. Monitor complete blood cell counts periodically during treatment according to manufacturer's prescribing information for background therapies. Consider withholding DARZALEX FASPRO ® until recovery of platelets. Embryo-Fetal Toxicity Based on the mechanism of action, DARZALEX FASPRO ® can cause fetal harm when administered to a pregnant woman. DARZALEX FASPRO ® may cause depletion of fetal immune cells and decreased bone density. Advise pregnant women of the potential risk to a fetus. Advise females with reproductive potential to use effective contraception during treatment with DARZALEX FASPRO ® and for 3 months after the last dose. The combination of DARZALEX FASPRO ® with lenalidomide, thalidomide, or pomalidomide is contraindicated in pregnant women because lenalidomide, thalidomide, and pomalidomide may cause birth defects and death of the unborn child. Refer to the lenalidomide, thalidomide, or pomalidomide prescribing information on use during pregnancy. Interference With Serological Testing Daratumumab binds to CD38 on red blood cells (RBCs) and results in a positive indirect antiglobulin test (indirect Coombs test). Daratumumab-mediated positive indirect antiglobulin test may persist for up to 6 months after the last daratumumab administration. Daratumumab bound to RBCs masks detection of antibodies to minor antigens in the patient's serum. The determination of a patient's ABO and Rh blood type are not impacted. Notify blood transfusion centers of this interference with serological testing and inform blood banks that a patient has received DARZALEX FASPRO ® . Type and screen patients prior to starting DARZALEX FASPRO ® . Interference With Determination of Complete Response Daratumumab is a human immunoglobulin G (IgG) kappa monoclonal antibody that can be detected on both the serum protein electrophoresis (SPE) and immunofixation (IFE) assays used for the clinical monitoring of endogenous M-protein. This interference can impact the determination of complete response and of disease progression in some DARZALEX FASPRO ® -treated patients with IgG kappa myeloma protein. ADVERSE REACTIONS In multiple myeloma, the most common adverse reaction (≥20%) with DARZALEX FASPRO ® monotherapy is upper respiratory tract infection. The most common adverse reactions with combination therapy (≥20% for any combination) include fatigue, nausea, diarrhea, dyspnea, insomnia, headache, pyrexia, cough, muscle spasms, back pain, vomiting, hypertension, upper respiratory tract infection, peripheral sensory neuropathy, constipation, pneumonia, and peripheral edema. The most common hematology laboratory abnormalities (≥40%) with DARZALEX FASPRO ® are decreased leukocytes, decreased lymphocytes, decreased neutrophils, decreased platelets, and decreased hemoglobin. Please click here to see the full Prescribing Information for DARZALEX FASPRO ® . About Johnson & Johnson At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com/ or at www.innovativemedicine.jnj.com . Follow us at @JanssenUS and @JNJInnovMed . Janssen Research & Development, LLC and Janssen Biotech, Inc. are both Johnson & Johnson companies. Cautions Concerning Forward-Looking Statements This press release contains "forward-looking statements" as defined in the Private Securities Litigation Reform Act of 1995 regarding product development and the potential benefits and treatment impact of TECVAYLI ® (teclistamab-cqyv ) and DARZALEX FASPRO ® (daratumumab and hyaluronidase-fihj). The reader is cautioned not to rely on these forward-looking statements. These statements are based on current expectations of future events. If underlying assumptions prove inaccurate or known or unknown risks or uncertainties materialize, actual results could vary materially from the expectations and projections of Janssen Research & Development, LLC, Janssen Biotech, Inc., and/or Johnson & Johnson. Risks and uncertainties include, but are not limited to: challenges and uncertainties inherent in product research and development, including the uncertainty of clinical success and of obtaining regulatory approvals; uncertainty of commercial success; manufacturing difficulties and delays; competition, including technological advances, new products and patents attained by competitors; challenges to patents; product efficacy or safety concerns resulting in product recalls or regulatory action; changes in behavior and spending patterns of purchasers of health care products and services; changes to applicable laws and regulations, including global health care reforms; and trends toward health care cost containment. A further list and descriptions of these risks, uncertainties and other factors can be found in Johnson & Johnson's Annual Report on Form 10-K for the fiscal year ended December 31, 2023 , including in the sections captioned "Cautionary Note Regarding Forward-Looking Statements" and "Item 1A. Risk Factors," and in Johnson & Johnson's subsequent Quarterly Reports on Form 10-Q and other filings with the Securities and Exchange Commission. Copies of these filings are available online at www.sec.gov , www.jnj.com or on request from Johnson & Johnson. None of Janssen Research & Development, LLC, Janssen Biotech, Inc. nor Johnson & Johnson undertake to update any forward-looking statement as a result of new information or future events or developments. * Marc S. Raab , M.D., has provided consulting, advisory, and speaking services to Johnson & Johnson; he has not been paid for any media work. 1 Raab, Marc, S., et al, 493 Phase 2 Study of Teclistamab-Based Induction Regimens in Patients with Transplant-Eligible (TE) Newly Diagnosed Multiple Myeloma (NDMM): Results from the GMMG-HD10/DSMM-XX (MajesTEC-5) Trial. 2024 American Society of Hematology Annual Meeting. December 2024 . 2 Zamagni, Elena, et al., 494 Phase 3 Study of Teclistamab (Tec) in Combination with Lenalidomide (Len) and Tec Alone Versus Len Alone in Newly Diagnosed Multiple Myeloma (NDMM) As Maintenance Therapy Following Autologous Stem Cell Transplantation (ASCT): Safety Run-in (SRI) Results from the MajesTEC-4/EMN30 Trial. 2024 American Society of Hematology Annual Meeting. December 2024 . 3 GMMG-HD10 / DSMM-XX / 64007957MMY2003, MajesTEC-5 (HD10/DSMMXX). https://clinicaltrials.gov/study/NCT05695508 . Accessed November 2024 . 4 Phase 3 Study of Teclistamab in Combination With Lenalidomide and Teclistamab Alone Versus Lenalidomide Alone in Participants With Newly Diagnosed Multiple Myeloma as Maintenance Therapy Following Autologous Stem Cell Transplantation (MajesTEC-4). https://clinicaltrials.gov/study/NCT05243797 . Accessed November 2024 . 5 A Study of Teclistamab in Combination With Daratumumab and Lenalidomide (Tec-DR) and Talquetamab in Combination With Daratumumab and Lenalidomide (Tal-DR) in Participants With Newly Diagnosed Multiple Myeloma (MajesTEC-7). https://classic.clinicaltrials.gov/ct2/show/NCT05552222 . Accessed November 2024 . 6 U.S. FDA Approves TECVAYLI ® (teclistamab-cqyv), the First Bispecific T-cell Engager Antibody for the Treatment of Patients with Relapsed or Refractory Multiple Myeloma. https://www.jnj.com/u-s-fda-approves-tecvayli-teclistamab-cqyv-the-first-bispecific-t-cell-engager-antibody-for-the-treatment-of-patients-with-relapsed-or-refractory-multiple-myeloma . Accessed November 2024 . 7 Rajkumar SV. Multiple myeloma: 2020 update on diagnosis, risk-stratification and management. Am J Hematol. 2020;95(5):548-5672020;95(5):548-567. http://www.ncbi.nlm.nih.gov/pubmed/32212178 8 National Cancer Institute. Plasma Cell Neoplasms. https://www.cancer.gov/types/myeloma/patient/myeloma-treatment-pdq . Accessed November 2024 . 9 City of Hope. Multiple Myeloma: Causes, Symptoms & Treatments. https://www.cancercenter.com/cancer-types/multiple-myeloma . Accessed November 2024 . 10 American Cancer Society. Key Statistics About Multiple Myeloma. https://www.cancer.org/cancer/multiple-myeloma/about/key-statistics.html#:~:text=Multiple%20myeloma%20is%20a%20relatively,men%20and%2015%2C370%20in%20women . Accessed November 2024 . 11 SEER Explorer: An interactive website for SEER cancer statistics [Internet]. Surveillance Research Program, National Cancer Institute. https://seer.cancer.gov/explorer/ . Accessed November 2024 . 12 American Cancer Society. What is Multiple Myeloma? https://www.cancer.org/cancer/multiple-myeloma/about/what-is-multiple-myeloma.html . Accessed November 2024 . 13 American Cancer Society. Multiple Myeloma Early Detection, Diagnosis, and Staging. https://www.cancer.org/cancer/types/multiple-myeloma/detection-diagnosis-staging/detection.html . Accessed November 2024 . Media contacts: Sarah Freeman sfreem21@its.jnj.com Christie Corbett ccorbet6@its.jnj.com Investor contact: Lauren Johnson investor-relations@its.jnj.com U.S. Medical Inquiries +1 800 526-7736 View original content to download multimedia: https://www.prnewswire.com/news-releases/tecvayli-teclistamab-cqyv-demonstrates-potential-as-frontline-combination-therapy-for-patients-with-newly-diagnosed-multiple-myeloma-302325575.html SOURCE Johnson & JohnsonNone
POUGHKEEPSIE, N.Y. (AP) — Elijah Lewis scored 21 points as Marist beat Binghamton 69-51 on Sunday. Read this article for free: Already have an account? To continue reading, please subscribe: * POUGHKEEPSIE, N.Y. (AP) — Elijah Lewis scored 21 points as Marist beat Binghamton 69-51 on Sunday. Read unlimited articles for free today: Already have an account? POUGHKEEPSIE, N.Y. (AP) — Elijah Lewis scored 21 points as Marist beat Binghamton 69-51 on Sunday. Lewis also had six rebounds and six assists for the Red Foxes (9-2). Josh Pascarelli added 15 points while shooting 6 for 12, including 2 for 5 from beyond the arc and grabbed seven rebounds. Jason Schofield shot 5 of 13 from the field to finish with 10 points. The Bearcats (8-7) were led by Ben Callahan-Gold, who posted 10 points. Gavin Walsh added nine points, 11 rebounds and three steals for Binghamton. Tymu Chenery had nine points and five assists. The loss snapped the Bearcats’ six-game winning streak. ___ The Associated Press created this story using technology provided by Data Skrive and data from Sportradar. AdvertisementT'Vondre Sweat's rookie season has already proven the Titans 100% right and the rest of the league wrong
Amazon is basically the internet’s secret stash of clever stuff, and we’ve rounded up 60 of the coolest finds you didn’t even know existed. These genius picks are all about upgrading your life, solving those little annoyances, or just making everyday things way easier—all without blowing your budget. Whether it’s a game-changing gadget or a tool you’ll wonder how you lived without, these affordable gems are perfect for gifting or treating yourself. Get ready to discover a whole new level of “how is this under $25?” A cordless table lamp you can take anywhere Take this literally anywhere you go and enjoy its multiple cool features—such as the stunning contemporary look, dimmable light, rechargeable design, and touch control operation. It comes with a USB cord and delivers up to 60 hours of light on a full charge whether you use it inside, out on the patio, or on a camping trip. These pastel highlighters that have a shimmery glitter effect If you love all things stationery, you will love these that create a shimmery glitter effect. The set includes an assortment of six pretty colors. Each highlighter has a chiseled tip that easily glides across the page and gives off just enough color without being too dark or bleeding through the paper. Use them to organize a planner, highlight important notes, and add a pop of vibrant color to your workspace. This portable electric lunch box that lets you heat up your lunch leftovers anywhere Skip eating out and bring your lunch to the office inside this clever that heats up the leftovers for you. It has a removable stainless steel container that’s dishwasher-safe, a silicone seal to prevent leaks, a built-in fork and spoon compartment, and a nifty carrying handle. The portable lunchbox takes about 30 minutes to heat up once plugged in and is a reviewer favorite that has garnered over 3,000 five-star ratings. A reusable windshield cleaner that works instantly Instantly clear mirrors and windows of steam, condensation, and grime with this reusable . The tool can be used wet or dry and won’t leave behind scratches on delicate surfaces. If it gets dirty, simply pop it in the washing machine. This LED backlit night light that has an overall rating of 4.8 out of 5 stars With close-to-perfect reviews to back it up, this has 16 LED bulbs to help add extra visibility during the night. It’s motion-activated, and can detect motion up to five meters away. After motion is no longer detected, it will turn itself off after 60 seconds. “This is the best motion sensor, plug in night light that we’ve tried. The backlighting is so gentle that getting back to sleep after you’ve been up in the night is much easier,” said one . A portable white noise machine with 16 sounds to choose from How cool is this tiny The portable gadget is so small it’ll fit right in your pocket, but it delivers maximum function with 16 different sounds and 32 volume levels to choose from, wireless operation, and four timer modes. Use it to fall asleep while away traveling or boost productivity during the work day — it’s a great little investment for its calming power. This set of scrub brushes that attach to your drill Power through cleaning by attaching this five-pack of to your drill. The set also comes with an attachment that extends your reach, making it easy to get into tight spaces. There are several versions of the brushes in the listing for cleaning various surfaces. This genius power strip with a built-in phone stand Charge up to six devices at once with this clever that has three three-pronged outlets, two USB-A outlets, and one USB-C outlet. The pyramid shape ensures plugs don’t block other outlets and it even has a built-in stand for your phone so you can see the screen while its charging. This set of stainless steel pruning sheers to trim plants & hedges Trim plants and hedges like a pro with this cheap yet efficient set of . The set includes gardening sheers with three types of stainless steel blades—straight, serrated, and curved—so you can trim everything from rose bushes to light branches. The sheers have ergonomic handles for comfortable use and a locking mechanism to prevent accidental cuts. A smooth faux leather keyboard mat with scratch-resistant suede backing Transform your home office with this that has suede backing for a nonslip grip. It has a smooth surface that eliminates the need for a mouse pad and is waterproof and easy to clean for maximum practicality. The mat protects your desk against scratches, stains, and spills and it’s available in multiple stylish colors to fit your work space. A tumbler lid organizer to declutter kitchen drawers Declutter kitchen drawers with this genius space-saving hack: a . Attach it to the bottom of a shelf or upper cabinet with the provided self-adhesive strips or mounting screws, and store up to five lids on each organizer. The streamlined stainless steel construction gives it a clean and modern look, and the organizer’s anti-drop design ensures lids stay put and don’t fall off. This easy-to-clean waterproof doormat to trap dirt before it enters your home Use this to trap dirt and keep your floors nice and clean. The mat has an absorbent top side and a nonslip bottom that prevents shifting, and you can easily clean it by shaking it off, rinsing it with water, or vacuuming it. It’s suitable for indoor and outdoor use, and besides being highly durable, its grooved pattern and beveled border add a lovely decorative accent to any space. A fridge deodorizer that lasts for 10 years Keep your fridge fresh for a whopping ten years with this . It’s made with diatomaceous earth to break down odors at their source. The compact tool can also be used in cars, closets, pantries, and more. An ice cube tray specifically designed for tumblers Chill your on-the-go drink with the help of this that’s specifically designed for tumblers. The silicone mold is designed to make three different-sized cylindrical ice cubes that are easy to release and have a slow melting speed. The tray has a flexible design, is simple to clean, and comes with a lid to prevent spills. A rechargeable handheld fan to keep you cool wherever you go Stay cool wherever you go with this that’s rechargeable and runs for up to 15 hours on a full charge. It’s compact enough to throw in your bag but has a powerful little motor that delivers a strong airflow and offers two speeds to choose from. Its folding design and portable weight mean you can easily carry it around or prop it up on your desk to keep you cool and refreshed all day long. This multi-purpose surface swiper that your countertops will thank you for With an overall score of 4.6 out of five stars, shoppers are loving this that comes with both a brush and a squeegee. The squeegee works to redirect spills and water puddles back into the sink, while the brush, equipped with nylon bristles, tackles crumbs. It’s an easy way to tackle small messes before they become more problematic. A bird bath fountain that’s conveniently solar-powered Instead of dealing with unsightly extension cords that mess up your landscaping, get this that doesn’t require an outlet. It features seven different nozzle styles so you can choose from a variety of spray scenes for your outdoor space. The bird bath’s glass panels reflect light and attract hummingbirds to drink and play in the fountain. This chamomile-flavored mouthwash for before bed An egg slicer with 3 different cutting modes that also works on fruits & veggies Save time, get uniform pieces, and make meal prep easier with this genius . It has sharp stainless steel blades that effortlessly cut through hard-boiled eggs (as well as fruits and veggies) and offers three slicing modes to choose from. A receptacle container maintains a clean worktop and allows you to transfer the chopped eggs into a dish easily. Once you’re done, simply toss the slicer in the dishwasher. These washable & reusable microfiber rags for a streak-free clean Clean any surface with these that deliver a streak-free clean and attract dust better than other materials. The lint-free rags are reusable, have seamless edges to prevent scratches, and come in a tissue box-style pack of 50 for easy dispensing. Best of all, they are machine-washable which makes them a more sustainable option for both the environment your wallet. Plus, it doesn’t hurt that you can get them in tons of fun colors from green to pink. This accurate meat thermometer with a devilish twist Who says a meat thermometer needs to be purely utilitarian? With this devilish , you’ll have a laugh in addition to perfectly cooked meats. The digital screen is easy to read and can be configured to Fahrenheit or Celsius. And the probe has a protective cover for the tip, so you can safely store it in a drawer or hang it on your fridge or grill with the magnetic back. This stainless steel rib rack that cooks meat more evenly Make sure your barbecue is a complete hit with this , which is designed to let both smoke and heat travel up either side for maximum flavor. These racks are strong and sturdy and can fit ribs of multiple sizes. They can help cook meat faster and more evenly, and couldn’t be easier to clean. Each pack comes with one rack that can hold up to five ribs. A soap dispenser & sponge holder to tidy up your kitchen counter Made from durable resin with a faux marble design that looks quite elevated, this is a three-in-one powerhouse for your kitchen. It’s a soap dispsner, sponge holder, and dish brush holder so all of your dishwashing essentials are together and nearby. It even comes with a nonslip pad on the bottom in case of any drips. A plastic pie carrier that keeps baked goods fresh Keep baked goods fresh inside this that has a hinged lid to create an airtight seal. It’s microwave, dishwasher, fridge, and freezer-safe for maximum practicality and in addition to pies, it can also be used for quiches, cookies, cakes, and other delicious bakes. The carrier is lightweight and easily portable and comes highly recommended by customers who comment on its great value and deep size. A drink organizer & dispenser with adjustable rows Make your fridge like the convenience store of your dreams with this drink . It features five rows that you can adjust to the width you need. What makes this especially useful is that it pushes your drinks right to the front as you grab one, keeping your items at the front of the fridge. No more lost, flat LaCroix for you. A long & slim drying wand for hard-to-reach areas Whether you’re cleaning a narrow tumbler or baby bottle, use this to get to the container’s hard-to-reach areas. It’s long enough to reach the base and slim enough to fit through a narrow opening, leaving no water spots and reducing gunk and scum buildup. The wand dries things quickly and efficiently, and it comes with three standard and three small individually wrapped, reusable drying heads. A portable iPhone charger you can use for 2 devices simultaneously Charge two devices simultaneously with this . The power bank delivers a 50% charge in just 40 minutes and its design cleverly doubles as a phone holder when taking selfies or watching videos. The charger is compact and lightweight for on-the-go use, making it perfect for travel or taking it to the office. These soundproof pads to prevent squeaking & wall damage Attach these to a headboard to prevent annoying squeaking and potential wall damage. The felt strips are self-adhesive and don’t require drilling, and they’re just the right size and thickness for a discreet look and maximum impact. Besides beds, you can also use them on sofas, armchairs, cabinets, and any other furniture that comes into contact with the wall. These pet grooming wipes for a quick clean between baths For a quick clean between baths, use these on your pet’s paws, face, and body. The plant-based wipes are infused with chamomile extract, vitamin E, and deodorizers to clean your furry pal, restore a shiny coat, and soothe sensitive skin. They’re large enough to cover a big surface area quickly and come in a resealable dispensing pouch so you can easily take them to the dog park or on a road trip. This anti-slip grippy pad that’s great to keep in your car Never lose your phone in the car again, thanks to this . Two pads come per pack, and they’re a great way to hold onto electronics and accessories ranging from remotes to eyeglasses. Crafted using malleable PU gel, each pad is reusable and easy to place. To install it, all you need to do is press down on it for five seconds. This fun game for grown-ups that’s a spin on a childhood classic If you loved UNO as a kid, get this that’s the grown-up version of the childhood favorite. It includes four different colored glasses made from shatterproof plastic for an adult twist on the classic, and they are conveniently dishwasher-safe for easy post-party cleanup. The game works the same way as the card version — get rid of your cards as fast as you can then shout DUNZO! A rotating nonslip phone mount that allows for full access while you ride Attach this to your bike and you’ll have full access to your phone while you ride. Its nonslip interior securely locks your phone in place without blocking the camera or buttons, and the mount rotates 360 degrees so you can choose the best viewing angle. In addition to a bike, you can also attach it to a motorcycle, treadmill, or stroller for ultimate versatility. These growing bags that support healthy roots Prevent root rot and support healthy growth with these breathable . They are constructed out of non-woven fabric, can be reused for multiple growing seasons, and have a sturdy structure thanks to a double-stitched design and reinforced handles. Use the bags for fruits, veggies, herbs, and flowers, whether inside, outside, or in a greenhouse. A lightweight survival tent to bring on your next hiking trip When you’re heading into the great outdoors, bring along this just in case you need it. The two-person tent folds into a lightweight bag that easily attaches to your backpack. Made from durable, waterproof polyester, the shelter helps trap your body heat and can protect you from wind, rain, and snow. These silicone spatulas that won’t scratch your cookware Use these to stir, scrape, and fold ingredients without scratching up your cookware. The four-piece set consists of a small, large, spoon, and jar spatula all of which are made of heat-resistant silicone that won’t melt or warp. The bendable heads allow for flexibility and the spatulas’ ergonomic design makes them lightweight yet sturdy enough to flip pancakes and mix cookie dough. A waterproof AirTag holder that slides onto your dog’s collar Keep tabs on your pup using an Apple AirTag and this that attaches to your dog’s collar. Available in various colors, the holder slides onto most collars and provides water and impact resistance for your tracker. Plus, the low-profile design creates a comfy fit that won’t dangle and disturb your dog during playtime. These adhesive pen holders so you never lose your tools Declutter and organize your workspace with these . They have an antislip design for a tight grip and feature two holes — one for a wider pen and another for a thinner pencil. To use them on a desk, wall, or fridge, wipe the surface clean, peel off the adhesive backing, then press the holder in place. According to one five-star , “The adhesive seems strong but hasn’t ruined any surfaces, which is always a worry of mine when attaching anything.” These mesh grill bags that prevent food from sticking to the grates Instead of using aluminum foil or oil on your grill, you can use these to prevent food from sticking and falling through the grates. Heat-resistant up to 500 degrees Fahrenheit, the bags can be used with gas, charcoal, and electric grills. They’re also built to last — just wash them with soap and water and use them for countless BBQ meals. These space-saving food containers that are lockable & leakproof Perfect for food prep or for storing the remainders of dinner, this set of will keep things locked and airtight. Designed to help you save precious pantry space, each of the five color-coded containers fit together to help you find exactly the size you’re looking for. They’re both freezer-safe and microwave-safe. These cabinet knobs with a fingerprint-proof finish for a cheap kitchen makeover For a quick and cheap kitchen makeover, get these that’ll instantly update your cabinets. They have a solid metal construction to withstand daily wear and tear and a fingerprint-proof finish for a neat look. The 20-piece set is easy to install and includes all the necessary hardware for the fastest home improvement project ever. You can also get them in satin nickel, oil rubbed bronze, and brass. This rust-proof magnetic paper towel holder to help clear your countertops Mount this on the fridge to clear countertops and maximize space in a small kitchen. It holds a standard roll of paper towels and is designed with square corners to stop them from unraveling. The holder is made from rust-proof stainless steel for durability and can also be attached to an outdoor grill, a microwave, or mounted inside a cabinet. This stainless steel kitchen composter that’s built to last If you’re looking to get into composting, this is a great way to start. Crafted from stainless steel and built to last a lifetime, this bin will hold days worth of compostable organic waste. It’s leakproof, easy to clean, and comes with a replaceable charcoal filter that will last up to six months. A cleaning solution & microfiber cloth to make your screens crystal clear again You probably don’t clean your screens and electronic devices as often as you should. With that said, you also shouldn’t use just anything to do the job. This has everything you need including a microfiber cloth and an alcohol-free solution in a 16-ounce spray bottle with over 1,500 sprays. Use it on laptop screens and monitors, tablets, phones, and more. A lightweight body wash to made with natural ingredients for sensitive skin Opt for this if you have dry, itchy, cracked, or flaky skin. It’s made with soothing essential oils like aloe vera, tea tree, and peppermint — as well as nourishing vitamins such as E and C that can treat common skin ailments including ringworm. The odor-eliminating properties will leave you with a fresh clean feeling that lasts all day. A phone for your car with MagSafe technology Regular phone mounts are already pretty ingenious. However, this uses MagSafe technology to hold your phone securely in place. It clips right onto your air vents and features 360-degree rotation. Simple, effective, and durable — this car mount checks all the boxes. This pop-up practice net for golf that you can assemble in your backyard Practice your golf swing from the comforts of your own home with this . Crafted from nylon with a pyramid design for the target, it only takes minutes to setup in a backyard or at a park. Great for lob shots, pitch shots, and flop shots, it also makes a great gift for the golf enthusiast in your life. This 2-pack of plate dividers perfect for picky eaters & runny food Whether you have a picky eater or just often serve up dishes that are delicious (but a little runny), these will do the trick. Also great for portion control and to help with motor skills, these dividers suction right to your plate. They’re available in three colors and will make you wonder why nobody thought to invent them sooner. This cute gnome dish brush that makes chores more fun Ditch the dull sponges in favor of this . Aside from being cute, it’s also sturdy, durable, and ready for some serious scrubbing. Arriving with its own drip tray, it’s designed with an ergonomic grip to make chores more fun as well as more comfortable. It’s also dishwasher-safe and makes a fantastic gift. This 7-piece set of stainless steel measuring spoons that won’t dent or bent A new set of is a great way to inspire yourself to bake more — and, this particular seven-piece set may even make the process a little easier. Crafted from stainless steel, these spoons are designed to not bend, break, crack, or hold onto the flavors of the ingredients you put inside. Engraved on each handle are measurements in both custom and metric form. The set even includes a leveler to help ensure you’re putting in the exact amount of ingredients for a better bake. This wireless doorbell with a battery life of up to 3 years This is a great way to greet guests. With a battery life of up to three years, it’s easy to install and is powerful enough to send a chime you’ll hear throughout your home. It comes with 52 different ringtones to choose from and four volume levels, making it easy to customize to your own preferences. A durable wooden board for creating charcuterie spreads This wooden is a must if you host and entertain often. It measures 18 inches long and 12 inches wide and has three deep grooved compartments with plenty of room to create a delectable charcuterie spread. Made from durable bamboo, this board is scratch-resistant and easy to clean — just use mild soap & warm water. This foot lotion that helps prevent sweaty, smelly feet If you’re concerned about sweaty or odorous feet, this can provide some peace of mind. Just a dime-sized amount of this lotion helps reduce sweat while soothing feet, made with eucalyptus oil and other moisturizing ingredients. Free from paragons, phthalates, formaldehydes, and sulfates — as well as cruelty free — this formula is gentle to use. “This product is worth the money,” one wrote. “I no longer have smelly, sweaty feet!” These cooling pads that keep your laptop slightly elevated Keep your laptop cool on the go using these that are easily portable. Magnetic and compact, the set of two pads allows your laptop to rest at a slight angle, letting air flow through and offering a comfortable typing angle. The silicone covering prevents scratches, and the bottom suction keeps your laptop from moving. These 4-in-1 pet grooming gloves that can help remove tricky knots Make bath time more enjoyable for you and your pet with these that are great for cats, dogs, and even horses. It’s a 4-in-1 product with the ability to help with grooming, de-shedding, bathing, and massaging. Each finger comes with long nubs to help gently eliminate deep knots, and they’re machine-washable for an easy clean when you’re done. The gloves are universally sized and a great way to de-shed your furry friend. These popular packing cubes that you can buy in 15 different colors Before your next vacation, you might want to grab a set of these . With eight cubes per set varying in size, they’ll help you stay more organized during your trip, especially if you’re sharing suitcase space with someone else. Each cube is designed from twill polyester, and each zippered cube contains mesh so that fabrics and belongings can breathe. You can get them in one of 15 colors. This double oven mitt shaped like a dachshund Avoid getting burned with this dog-shaped , which protects both hands while you’re cooking or baking. With the ability to withstand heat up to 482 degrees Fahrenheit, you can feel more assured while creating meals that require higher temperatures. Since it’s made with cotton, you’ll get a good amount of flexibility while they’re in use. These grocery bag handles that can support up to 80 pounds of merchandise Get a better handle on your groceries with this . With the ability to support up to 80 pounds of goods, these holders will give you more of a comfortable grip than you would have without them. They’re heavy-duty, incredibly well-reviewed, and a great way to ensure you don’t have to make multiple trips back to your car on grocery day. This insulated nylon bag that can hold approximately 24 cans This is insulated to help ensure the drinks and snacks that you bring with you on vacation or during a hike stay as fresh and cold as possible. Its design includes an adjustable air valve which gives you a little more control over how insulated you’d prefer the bag to be. Available in two colors and sizes, both are capable of holding approximately 24 cans in total.
Percentages: FG .391, FT .714. 3-Point Goals: 3-14, .214 (Finister 1-1, Huefner 1-3, Wilkerson 1-8, Boykin 0-1, Hammons 0-1). Team Rebounds: 3. Team Turnovers: None. Blocked Shots: 3 (Sakho 2, Boykin). Turnovers: 9 (Boykin 2, Huefner 2, Scroggins 2, Burns, Finister, Sakho). Steals: 7 (Boykin 4, Finister, Hammons, Wilkerson). Technical Fouls: Scroggins, 15:54 second. Percentages: FG .396, FT .773. 3-Point Goals: 7-24, .292 (Tate 3-6, Conners 2-5, Threadgill 1-3, Huntley 1-5, Beaubrun 0-1, Dodd 0-1, Muttilib 0-3). Team Rebounds: 4. Team Turnovers: 1. Blocked Shots: 3 (Wilson 2, Beaubrun). Turnovers: 11 (Tate 5, Wilson 3, Beaubrun, Dodd, Huntley). Steals: 4 (Huntley, Muttilib, Tate, Threadgill). Technical Fouls: None. .ATLANTA — Jimmy Carter, the peanut farmer who won the presidency in the wake of the Watergate scandal and Vietnam War, endured humbling defeat after one tumultuous term and then redefined life after the White House as a global humanitarian, has died. He was 100 years old. The longest-lived American president died on Sunday, more than a year after entering hospice care, at his home in the small town of Plains, Georgia, where he and his wife, Rosalynn, who died at 96 in November 2023, spent most of their lives, The Carter Center said. “Our founder, former U.S. President Jimmy Carter, passed away this afternoon in Plains, Georgia,” the center said in a posting about his death on the social media platform X. It added in a statement that he died peacefully, surrounded by his family. As reaction poured in from around the world, President Joe Biden mourned Carter’s death, saying the world lost an “extraordinary leader, statesman and humanitarian” and he lost a dear friend. Biden cited Carter’s compassion and moral clarity, his work to eradicate disease, forge peace, advance civil and human rights, promote free and fair elections, house the homeless and advocacy for the disadvantaged as an example for others. “To all of the young people in this nation and for anyone in search of what it means to live a life of purpose and meaning — the good life — study Jimmy Carter, a man of principle, faith and humility,” Biden said in a statement. “He showed that we are a great nation because we are a good people — decent and honorable, courageous and compassionate, humble and strong.” Biden said he is ordering a state funeral for Carter in Washington. Businessman, Navy officer, evangelist, politician, negotiator, author, woodworker, citizen of the world — Carter forged a path that still challenges political assumptions and stands out among the 45 men who reached the nation’s highest office. The 39th president leveraged his ambition with a keen intellect, deep religious faith and prodigious work ethic, conducting diplomatic missions into his 80s and building houses for the poor well into his 90s. “My faith demands — this is not optional — my faith demands that I do whatever I can, wherever I am, whenever I can, for as long as I can, with whatever I have to try to make a difference,” Carter once said. A moderate Democrat, Carter entered the 1976 presidential race as a little-known Georgia governor with a broad smile, outspoken Baptist mores and technocratic plans reflecting his education as an engineer. His no-frills campaign depended on public financing, and his promise not to deceive the American people resonated after Richard Nixon’s disgrace and U.S. defeat in southeast Asia. “If I ever lie to you, if I ever make a misleading statement, don’t vote for me. I would not deserve to be your president,” Carter repeated before narrowly beating Republican incumbent Gerald Ford, who had lost popularity pardoning Nixon. Carter governed amid Cold War pressures, turbulent oil markets and social upheaval over racism, women’s rights and America’s global role. His most acclaimed achievement in office was a Mideast peace deal that he brokered by keeping Egyptian president Anwar Sadat and Israeli prime minister Menachem Begin at the bargaining table for 13 days in 1978. That Camp David experience inspired the post-presidential center where Carter would establish so much of his legacy. Yet Carter’s electoral coalition splintered under double-digit inflation, gasoline lines and the 444-day hostage crisis in Iran. His bleakest hour came when eight Americans died in a failed hostage rescue in April 1980, helping to ensure his landslide defeat to Republican Ronald Reagan. Carter acknowledged in his 2020 “White House Diary” that he could be “micromanaging” and “excessively autocratic,” complicating dealings with Congress and the federal bureaucracy. He also turned a cold shoulder to Washington’s news media and lobbyists, not fully appreciating their influence on his political fortunes. “It didn’t take us long to realize that the underestimation existed, but by that time we were not able to repair the mistake,” Carter told historians in 1982, suggesting that he had “an inherent incompatibility” with Washington insiders. Carter insisted his overall approach was sound and that he achieved his primary objectives — to “protect our nation’s security and interests peacefully” and “enhance human rights here and abroad” — even if he fell spectacularly short of a second term. Ignominious defeat, though, allowed for renewal. The Carters founded The Carter Center in 1982 as a first-of-its-kind base of operations, asserting themselves as international peacemakers and champions of democracy, public health and human rights. “I was not interested in just building a museum or storing my White House records and memorabilia,” Carter wrote in a memoir published after his 90th birthday. “I wanted a place where we could work.” That work included easing nuclear tensions in North and South Korea, helping to avert a U.S. invasion of Haiti and negotiating cease-fires in Bosnia and Sudan. By 2022, The Carter Center had declared at least 113 elections in Latin America, Asia and Africa to be free or fraudulent. Recently, the center began monitoring U.S. elections as well. Carter’s stubborn self-assuredness and even self-righteousness proved effective once he was unencumbered by the Washington order, sometimes to the point of frustrating his successors. He went “where others are not treading,” he said, to places like Ethiopia, Liberia and North Korea, where he secured the release of an American who had wandered across the border in 2010. “I can say what I like. I can meet whom I want. I can take on projects that please me and reject the ones that don’t,” Carter said. He announced an arms-reduction-for-aid deal with North Korea without clearing the details with Bill Clinton’s White House. He openly criticized President George W. Bush for the 2003 invasion of Iraq. He also criticized America’s approach to Israel with his 2006 book “Palestine: Peace Not Apartheid.” And he repeatedly countered U.S. administrations by insisting North Korea should be included in international affairs, a position that most aligned Carter with Republican President Donald Trump. Among the center’s many public health initiatives, Carter vowed to eradicate the guinea worm parasite during his lifetime, and nearly achieved it: Cases dropped from millions in the 1980s to nearly a handful. With hardhats and hammers, the Carters also built homes with Habitat for Humanity. The Nobel committee’s 2002 Peace Prize cites his “untiring effort to find peaceful solutions to international conflicts, to advance democracy and human rights, and to promote economic and social development.” Carter should have won it alongside Sadat and Begin in 1978, the chairman added. Carter accepted the recognition saying there was more work to be done. “The world is now, in many ways, a more dangerous place,” he said. “The greater ease of travel and communication has not been matched by equal understanding and mutual respect.” Carter’s globetrotting took him to remote villages where he met little “Jimmy Carters,” so named by admiring parents. But he spent most of his days in the same one-story Plains house — expanded and guarded by Secret Service agents — where the Carters lived before he became governor. He regularly taught Sunday school lessons at Maranatha Baptist Church until his mobility declined and the coronavirus pandemic raged. Those sessions drew visitors from around the world to the small sanctuary where Carter will receive his final send-off after a state funeral at Washington’s National Cathedral. The common assessment that he was a better ex-president than president rankled Carter and his allies. His prolific post-presidency gave him a brand above politics, particularly for Americans too young to witness him in office. But Carter also lived long enough to see biographers and historians reassess his White House years more generously. His record includes the deregulation of key industries, reduction of U.S. dependence on foreign oil, cautious management of the national debt and notable legislation on the environment, education and mental health. He focused on human rights in foreign policy, pressuring dictators to release thousands of political prisoners. He acknowledged America’s historical imperialism, pardoned Vietnam War draft evaders and relinquished control of the Panama Canal. He normalized relations with China. “I am not nominating Jimmy Carter for a place on Mount Rushmore,” Stuart Eizenstat, Carter’s domestic policy director, wrote in a 2018 book. “He was not a great president” but also not the “hapless and weak” caricature voters rejected in 1980, Eizenstat said. Rather, Carter was “good and productive” and “delivered results, many of which were realized only after he left office.” Madeleine Albright, a national security staffer for Carter and Clinton’s secretary of state, wrote in Eizenstat’s forward that Carter was “consequential and successful” and expressed hope that “perceptions will continue to evolve” about his presidency. “Our country was lucky to have him as our leader,” said Albright, who died in 2022. Jonathan Alter, who penned a comprehensive Carter biography published in 2020, said in an interview that Carter should be remembered for “an epic American life” spanning from a humble start in a home with no electricity or indoor plumbing through decades on the world stage across two centuries. “He will likely go down as one of the most misunderstood and underestimated figures in American history,” Alter told The Associated Press. James Earl Carter Jr. was born Oct. 1, 1924, in Plains and spent his early years in nearby Archery. His family was a minority in the mostly Black community, decades before the civil rights movement played out at the dawn of Carter’s political career. Carter, who campaigned as a moderate on race relations but governed more progressively, talked often of the influence of his Black caregivers and playmates but also noted his advantages: His land-owning father sat atop Archery’s tenant-farming system and owned a main street grocery. His mother, Lillian, would become a staple of his political campaigns. Seeking to broaden his world beyond Plains and its population of fewer than 1,000 — then and now — Carter won an appointment to the U.S. Naval Academy, graduating in 1946. That same year he married Rosalynn Smith, another Plains native, a decision he considered more important than any he made as head of state. She shared his desire to see the world, sacrificing college to support his Navy career. Carter climbed in rank to lieutenant, but then his father was diagnosed with cancer, so the submarine officer set aside his ambitions of admiralty and moved the family back to Plains. His decision angered Rosalynn, even as she dived into the peanut business alongside her husband. Carter again failed to talk with his wife before his first run for office — he later called it “inconceivable” not to have consulted her on such major life decisions — but this time, she was on board. “My wife is much more political,” Carter told the AP in 2021. He won a state Senate seat in 1962 but wasn’t long for the General Assembly and its back-slapping, deal-cutting ways. He ran for governor in 1966 — losing to arch-segregationist Lester Maddox — and then immediately focused on the next campaign. Carter had spoken out against church segregation as a Baptist deacon and opposed racist “Dixiecrats” as a state senator. Yet as a local school board leader in the 1950s he had not pushed to end school segregation even after the Supreme Court's Brown v. Board of Education decision, despite his private support for integration. And in 1970, Carter ran for governor again as the more conservative Democrat against Carl Sanders, a wealthy businessman Carter mocked as “Cufflinks Carl.” Sanders never forgave him for anonymous, race-baiting fliers, which Carter disavowed. Ultimately, Carter won his races by attracting both Black voters and culturally conservative whites. Once in office, he was more direct. “I say to you quite frankly that the time for racial discrimination is over,” he declared in his 1971 inaugural address, setting a new standard for Southern governors that landed him on the cover of Time magazine. His statehouse initiatives included environmental protection, boosting rural education and overhauling antiquated executive branch structures. He proclaimed Martin Luther King Jr. Day in the slain civil rights leader’s home state. And he decided, as he received presidential candidates in 1972, that they were no more talented than he was. In 1974, he ran Democrats’ national campaign arm. Then he declared his own candidacy for 1976. An Atlanta newspaper responded with the headline: “Jimmy Who?” The Carters and a “Peanut Brigade” of family members and Georgia supporters camped out in Iowa and New Hampshire, establishing both states as presidential proving grounds. His first Senate endorsement: a young first-termer from Delaware named Joe Biden. Yet it was Carter’s ability to navigate America’s complex racial and rural politics that cemented the nomination. He swept the Deep South that November, the last Democrat to do so, as many white Southerners shifted to Republicans in response to civil rights initiatives. A self-declared “born-again Christian,” Carter drew snickers by referring to Scripture in a Playboy magazine interview, saying he “had looked on many women with lust. I’ve committed adultery in my heart many times.” The remarks gave Ford a new foothold and television comedians pounced — including NBC’s new “Saturday Night Live” show. But voters weary of cynicism in politics found it endearing. Carter chose Minnesota U.S. Sen. Walter “Fritz” Mondale as his running mate on a “Grits and Fritz” ticket. In office, he elevated the vice presidency and the first lady’s office. Mondale’s governing partnership was a model for influential successors Al Gore, Dick Cheney and Biden. Rosalynn Carter was one of the most involved presidential spouses in history, welcomed into Cabinet meetings and huddles with lawmakers and top aides. The Carters presided with uncommon informality: He used his nickname “Jimmy” even when taking the oath of office, carried his own luggage and tried to silence the Marine Band’s “Hail to the Chief.” They bought their clothes off the rack. Carter wore a cardigan for a White House address, urging Americans to conserve energy by turning down their thermostats. Amy, the youngest of four children, attended District of Columbia public school. Washington’s social and media elite scorned their style. But the larger concern was that “he hated politics,” according to Eizenstat, leaving him nowhere to turn politically once economic turmoil and foreign policy challenges took their toll. Carter partially deregulated the airline, railroad and trucking industries and established the departments of Education and Energy, and the Federal Emergency Management Agency. He designated millions of acres of Alaska as national parks or wildlife refuges. He appointed a then-record number of women and nonwhite people to federal posts. He never had a Supreme Court nomination, but he elevated civil rights attorney Ruth Bader Ginsburg to the nation’s second highest court, positioning her for a promotion in 1993. He appointed Paul Volker, the Federal Reserve chairman whose policies would help the economy boom in the 1980s — after Carter left office. He built on Nixon’s opening with China, and though he tolerated autocrats in Asia, pushed Latin America from dictatorships to democracy. But he couldn’t immediately tame inflation or the related energy crisis. And then came Iran. After he admitted the exiled Shah of Iran to the U.S. for medical treatment, the American Embassy in Tehran was overrun in 1979 by followers of the Ayatollah Ruhollah Khomeini. Negotiations to free the hostages broke down repeatedly ahead of the failed rescue attempt. The same year, Carter signed SALT II, the new strategic arms treaty with Leonid Brezhnev of the Soviet Union, only to pull it back, impose trade sanctions and order a U.S. boycott of the Moscow Olympics after the Soviets invaded Afghanistan. Hoping to instill optimism, he delivered what the media dubbed his “malaise” speech, although he didn’t use that word. He declared the nation was suffering “a crisis of confidence.” By then, many Americans had lost confidence in the president, not themselves. Carter campaigned sparingly for reelection because of the hostage crisis, instead sending Rosalynn as U.S. Sen. Edward M. Kennedy challenged him for the Democratic nomination. Carter famously said he’d “kick his ass,” but was hobbled by Kennedy as Reagan rallied a broad coalition with “make America great again” appeals and asking voters whether they were “better off than you were four years ago.” Reagan further capitalized on Carter’s lecturing tone, eviscerating him in their lone fall debate with the quip: “There you go again.” Carter lost all but six states and Republicans rolled to a new Senate majority. Carter successfully negotiated the hostages’ freedom after the election, but in one final, bitter turn of events, Tehran waited until hours after Carter left office to let them walk free. At 56, Carter returned to Georgia with “no idea what I would do with the rest of my life.” Four decades after launching The Carter Center, he still talked of unfinished business. “I thought when we got into politics we would have resolved everything,” Carter told the AP in 2021. “But it’s turned out to be much more long-lasting and insidious than I had thought it was. I think in general, the world itself is much more divided than in previous years.” Still, he affirmed what he said when he underwent treatment for a cancer diagnosis in his 10th decade of life. “I’m perfectly at ease with whatever comes,” he said in 2015. “I’ve had a wonderful life. I’ve had thousands of friends, I’ve had an exciting, adventurous and gratifying existence.” Sanz is a former Associated Press reporter.Modular Construction Market in the US to grow by USD 7.37 Billion (2024-2028), with on-site constraints boosting revenue; Report on AI-driven market evolution - TechnavioWASHINGTON — The National Park Service is seeing a surge in private support bigger than anytime in its 108-year history as it also faces a maintenance backlog of more than $23 billion, made worse this fall by hurricane damage to its most popular location. Three years after setting a goal of raising $1 billion, the Park Service’s official charitable partner, the National Park Foundation, is almost there, having raised $840 million since 2021, the foundation’s outgoing president and CEO Will Shafroth said. That fundraising under the Campaign for National Parks is in addition to efforts of park partners across the country — such as the Trust for Public Land, American Battlefield Trust, Conservation Legacy and the Student Conservation Association — that collectively want to raise another $3.5 billion. Visits to national parks rose from about 275 million in 2010 to 325 million last year. Shafroth said many of these visitors, inspired by the beauty of places like Yellowstone National Park, say the parks and staff have “created an amazing experience for me and my family. I want to give back.” Hundreds of thousands more give back by volunteering, whether rebuilding trails, clearing trash, serving as docents or organizing special events. “National parks experienced substantially increased public interest over the past two years,” according to the 2024 Park Partners Report commissioned by the foundation. There are now at least 470 partner groups, many of them “Friends” organizations that coordinate volunteer work with superintendents of individual parks. That community provided nearly 1 million volunteer hours in the park system last year, the equivalent of 122,500 days or 471 full-time employees, according to the report. One of those groups is Friends of the Smokies, which has about 2,000 members who volunteer for projects in Great Smoky Mountains National Park in North Carolina and Tennessee, the most popular of the 63 national parks with 13.3 million visitors in 2023. The park, which stretches over 816 square miles, sustained extensive damage from Hurricane Helene in late September, and many roads and trails are still closed to the public, said Dana Soehn, president of Friends of the Smokies. But the group is eager to get to work when the Park Service completes its assessments and makes restoration plans, she said. “We stand at the ready to really push and raise funds,” Soehn said. “The public-private partnership in helping meet these challenging times is something that’s critically needed. Our organization is able to provide $2 million to $4 million of funding each year to help support the national park.” Funding needs The private funding goes a long way to help the cash-strapped National Park Service, with an operating budget of $3.3 billion in fiscal 2024, which supports about 20,000 full-time employees. The Senate’s Interior-Environment Appropriations bill would provide $3.5 billion in fiscal 2025, as the Biden administration requested, but the House version would cut the funding to $3.1 billion. The Great American Outdoors Act passed by Congress in 2020 provided up to $1.3 billion per year for five years through 2025 to help reduce $23.3 billion in deferred maintenance projects. Private donations won’t do much to reduce the maintenance backlog because most people aren’t interested in funding infrastructure projects like roads and bridges that are the government’s responsibility, Shafroth said. “We’re never going to be very effective at convincing donors to pay for pothole repair and water systems and things like that,” he said. “So we really need to focus on the things that are resonant to donors and also are a high need for the parks.” When Lilly Endowment Inc. announced a $100 million contribution in August, Shafroth’s foundation said the funds would go toward four priorities: creating environmental stewardship opportunities for young people, protecting fragile ecosystems and diverse species in the parks, developing new technologies to improve visitor experiences, and providing “a more comprehensive historical narrative” about national parks and the communities around them. Many donors to the park system, especially corporate givers, are also motivated by the knowledge that public lands used for recreation are an economic driver. Outdoor recreation generates $1.2 trillion in annual economic activity and supports 5 million jobs, according to a report released in November by the Outdoor Recreation Roundtable using data from the U.S. Commerce Department’s Bureau of Economic Analysis. The ORR is a coalition of more than 110,000 businesses in the sector. The Interior Department reported last year that visitor spending in communities near national parks totals more than $50 billion a year, supporting nearly 400,000 jobs. Other legislation Advocates for the parks are urging Congress to rev up this economic engine by passing a package of bills that would overhaul how public land agencies distribute passes and permits, encourage technology to improve visitor experiences, restore campgrounds and address housing shortages near outdoor recreation areas, among other things. The House passed the legislation sponsored by Natural Resources Chairman Bruce Westerman, R-Ark., in April by voice vote under suspension of the rules. Dozens of groups are urging the Senate to pass the measure in the lame-duck session. “Despite the profound and widespread benefits that parks and outdoor recreation offer, they are chronically underfunded with many systems facing a significant backlog of capital improvement projects,” more than 50 organizations said in a Nov. 12 letter to Senate leaders urging them to prioritize the legislation. Aside from their economic importance, Shafroth noted that national parks play a role in uniting Americans. “You know, our country just feels so divided in so many ways, especially politically,” he said. “It feels like those divisions just dissolve when people enter a national park. They’re just citizens of the United States. They’re just lovers of the outdoors, appreciators of America’s story.” Shafroth announced this fall that he plans to step aside as president and CEO of the National Park Foundation and turn over the reins to Park Service veteran Jeff Reinbold, most recently the superintendent of the National Mall and Memorial Parks in Washington. The pair will work together on the transition in December and January, then Shafroth said he plans to develop a new program at the foundation addressing issues facing the park system, including climate change, housing shortages near parks and development of new technologies.
NoneIwi of Origin: Calling all Māori across Tāmaki Makaurau to celebrate your health and wellbeing – Mere Rangihuna
Martin scores 17, Southeast Missouri State beats Westminster (MO) 88-39Luke Williams feels Swansea ‘lost grip’ on game despite sealing victory at Derby
Oklahoma’s keys to victory against AlabamaWASHINGTON — President-elect Donald Trump's transition team on Tuesday signed an agreement to allow the Justice Department to conduct background checks on his nominees and appointees after a weekslong delay. The step lets Trump transition aides and future administration staffers obtain security clearances before Inauguration Day to access classified information about ongoing government programs, an essential step for a smooth transition of power. It also allows those nominees who are up for Senate confirmation to face the background checks lawmakers want before voting on them. Teams of investigators have been standing by to process clearances for Trump aides and advisers. FILE - Susie Wiles watches as Republican presidential candidate former President Donald Trump speaks at a caucus night party in Des Moines, Iowa, Jan. 15, 2024. (AP Photo/Andrew Harnik, File) "This agreement with the Department of Justice will ensure President Trump and his team are ready on Day 1 to begin enacting the America First Agenda that an overwhelming majority of our nation supported on Election Day," said Susie Wiles, Trump's designate to be White House chief of staff. The announcement came a week after the Trump transition team signed an agreement with the Biden White House to allow transition staff to coordinate with the existing federal workforce before taking office Jan. 20. The White House agreement was supposed to have been signed by Oct. 1, according to the Presidential Transition Act, and the Biden White House issued both public and private appeals for Trump's team to sign on. Security clearances are required to access classified information, including on ongoing operations and threats to the nation, and the Biden White House and outside experts emphasized to Trump's team the importance of having cleared personnel before Inauguration Day so they could be fully briefed and ready to run the government. President-elect Donald Trump arrives before the launch of the sixth test flight of the SpaceX Starship rocket Tuesday, Nov. 19, 2024 in Boca Chica, Texas. (Brandon Bell/Pool via AP) Republican Senators also insisted on FBI background checks for Trump's nominees before they face confirmation votes, as has been standard practice for decades. Lawmakers were particularly interested in seeing the findings of reviews into Trump's designated nominee for defense secretary, former Fox News host Pete Hegseth, and for Rep. Tulsi Gabbard to be director of national intelligence. "That's why it's so important that we have an FBI background check, a committee review of extensive questions and questionnaires, and a public hearing," Sen. Susan Collins, R-Maine, said Monday. John Thune, incoming Senate Republican leader, said the Trump team "understands there's going to have to be a thorough vetting of all these nominees." Among President-elect Donald Trump's picks are Susie Wiles for chief of staff, Florida Sen. Marco Rubio for secretary of state, former Democratic House member Tulsi Gabbard for director of national intelligence and Florida Rep. Matt Gaetz for attorney general. Susie Wiles, 67, was a senior adviser to Trump's 2024 presidential campaign and its de facto manager. Trump named Florida Sen. Marco Rubio to be secretary of state, making a former sharp critic his choice to be the new administration's top diplomat. Rubio, 53, is a noted hawk on China, Cuba and Iran, and was a finalist to be Trump's running mate on the Republican ticket last summer. Rubio is the vice chairman of the Senate Intelligence Committee and a member of the Senate Foreign Relations Committee. “He will be a strong Advocate for our Nation, a true friend to our Allies, and a fearless Warrior who will never back down to our adversaries,” Trump said of Rubio in a statement. The announcement punctuates the hard pivot Rubio has made with Trump, whom the senator called a “con man" during his unsuccessful campaign for the 2016 GOP presidential nomination. Their relationship improved dramatically while Trump was in the White House. And as Trump campaigned for the presidency a third time, Rubio cheered his proposals. For instance, Rubio, who more than a decade ago helped craft immigration legislation that included a path to citizenship for people in the U.S. illegally, now supports Trump's plan to use the U.S. military for mass deportations. Pete Hegseth, 44, is a co-host of Fox News Channel’s “Fox & Friends Weekend” and has been a contributor with the network since 2014, where he developed a friendship with Trump, who made regular appearances on the show. Hegseth lacks senior military or national security experience. If confirmed by the Senate, he would inherit the top job during a series of global crises — ranging from Russia’s war in Ukraine and the ongoing attacks in the Middle East by Iranian proxies to the push for a cease-fire between Israel, Hamas and Hezbollah and escalating worries about the growing alliance between Russia and North Korea. Hegseth is also the author of “The War on Warriors: Behind the Betrayal of the Men Who Keep Us Free,” published earlier this year. Trump tapped Pam Bondi, 59, to be attorney general after U.S. Rep. Matt Gaetz withdrew his name from consideration. She was Florida's first female attorney general, serving between 2011 and 2019. She also was on Trump’s legal team during his first impeachment trial in 2020. Considered a loyalist, she served as part of a Trump-allied outside group that helped lay the groundwork for his future administration called the America First Policy Institute. Bondi was among a group of Republicans who showed up to support Trump at his hush money criminal trial in New York that ended in May with a conviction on 34 felony counts. A fierce defender of Trump, she also frequently appears on Fox News and has been a critic of the criminal cases against him. Trump picked South Dakota Gov. Kristi Noem, a well-known conservative who faced sharp criticism for telling a story in her memoir about shooting a rambunctious dog, to lead an agency crucial to the president-elect’s hardline immigration agenda. Noem used her two terms leading a tiny state to vault to a prominent position in Republican politics. South Dakota is usually a political afterthought. But during the COVID-19 pandemic, Noem did not order restrictions that other states had issued and instead declared her state “open for business.” Trump held a fireworks rally at Mount Rushmore in July 2020 in one of the first large gatherings of the pandemic. She takes over a department with a sprawling mission. In addition to key immigration agencies, the Department of Homeland Security oversees natural disaster response, the U.S. Secret Service, and Transportation Security Administration agents who work at airports. The governor of North Dakota, who was once little-known outside his state, Burgum is a former Republican presidential primary contender who endorsed Trump, and spent months traveling to drum up support for him, after dropping out of the race. Burgum was a serious contender to be Trump’s vice presidential choice this summer. The two-term governor was seen as a possible pick because of his executive experience and business savvy. Burgum also has close ties to deep-pocketed energy industry CEOs. Trump made the announcement about Burgum joining his incoming administration while addressing a gala at his Mar-a-Lago club, and said a formal statement would be coming the following day. In comments to reporters before Trump took the stage, Burgum said that, in recent years, the power grid is deteriorating in many parts of the country, which he said could raise national security concerns but also drive up prices enough to increase inflation. “There's just a sense of urgency, and a sense of understanding in the Trump administration,” Burgum said. Robert F. Kennedy Jr. ran for president as a Democrat, than as an independent, and then endorsed Trump . He's the son of Democratic icon Robert Kennedy, who was assassinated during his own presidential campaign. The nomination of Kennedy to lead the Department of Health and Human Services alarmed people who are concerned about his record of spreading unfounded fears about vaccines . For example, he has long advanced the debunked idea that vaccines cause autism. Scott Bessent, 62, is a former George Soros money manager and an advocate for deficit reduction. He's the founder of hedge fund Key Square Capital Management, after having worked on-and-off for Soros Fund Management since 1991. If confirmed by the Senate, he would be the nation’s first openly gay treasury secretary. He told Bloomberg in August that he decided to join Trump’s campaign in part to attack the mounting U.S. national debt. That would include slashing government programs and other spending. “This election cycle is the last chance for the U.S. to grow our way out of this mountain of debt without becoming a sort of European-style socialist democracy,” he said then. Scott Turner is a former NFL player and White House aide. He ran the White House Opportunity and Revitalization Council during Trump’s first term in office. Trump, in a statement, credited Turner, the highest-ranking Black person he’s yet selected for his administration, with “helping to lead an Unprecedented Effort that Transformed our Country’s most distressed communities.” Sean Duffy is a former House member from Wisconsin who was one of Trump's most visible defenders on cable news. Duffy served in the House for nearly nine years, sitting on the Financial Services Committee and chairing the subcommittee on insurance and housing. He left Congress in 2019 for a TV career and has been the host of “The Bottom Line” on Fox Business. Before entering politics, Duffy was a reality TV star on MTV, where he met his wife, “Fox and Friends Weekend” co-host Rachel Campos-Duffy. They have nine children. A campaign donor and CEO of Denver-based Liberty Energy, Write is a vocal advocate of oil and gas development, including fracking — a key pillar of Trump’s quest to achieve U.S. “energy dominance” in the global market. Wright also has been one of the industry’s loudest voices against efforts to fight climate change. He said the climate movement around the world is “collapsing under its own weight.” The Energy Department is responsible for advancing energy, environmental and nuclear security of the United States. Wright also won support from influential conservatives, including oil and gas tycoon Harold Hamm. Hamm, executive chairman of Oklahoma-based Continental Resources, a major shale oil company, is a longtime Trump supporter and adviser who played a key role on energy issues in Trump’s first term. President-elect Donald Trump tapped billionaire professional wrestling mogul Linda McMahon to be secretary of the Education Department, tasked with overseeing an agency Trump promised to dismantle. McMahon led the Small Business Administration during Trump’s initial term from 2017 to 2019 and twice ran unsuccessfully as a Republican for the U.S. Senate in Connecticut. She’s seen as a relative unknown in education circles, though she expressed support for charter schools and school choice. She served on the Connecticut Board of Education for a year starting in 2009 and has spent years on the board of trustees for Sacred Heart University in Connecticut. Brooke Rollins, who graduated from Texas A&M University with a degree in agricultural development, is a longtime Trump associate who served as White House domestic policy chief during his first presidency. The 52-year-old is president and CEO of the America First Policy Institute, a group helping to lay the groundwork for a second Trump administration. She previously served as an aide to former Texas Gov. Rick Perry and ran a think tank, the Texas Public Policy Foundation. Trump chose Howard Lutnick, head of brokerage and investment bank Cantor Fitzgerald and a cryptocurrency enthusiast, as his nominee for commerce secretary, a position in which he'd have a key role in carrying out Trump's plans to raise and enforce tariffs. Trump made the announcement Tuesday on his social media platform, Truth Social. Lutnick is a co-chair of Trump’s transition team, along with Linda McMahon, the former wrestling executive who previously led Trump’s Small Business Administration. Both are tasked with putting forward candidates for key roles in the next administration. The nomination would put Lutnick in charge of a sprawling Cabinet agency that is involved in funding new computer chip factories, imposing trade restrictions, releasing economic data and monitoring the weather. It is also a position in which connections to CEOs and the wider business community are crucial. Doug Collins is a former Republican congressman from Georgia who gained recognition for defending Trump during his first impeachment trial, which centered on U.S. assistance for Ukraine. Trump was impeached for urging Ukraine to investigate Joe Biden in 2019 during the Democratic presidential nomination, but he was acquitted by the Senate. Collins has also served in the armed forces himself and is currently a chaplain in the United States Air Force Reserve Command. "We must take care of our brave men and women in uniform, and Doug will be a great advocate for our Active Duty Servicemembers, Veterans, and Military Families to ensure they have the support they need," Trump said in a statement about nominating Collins to lead the Department of Veterans Affairs. Karoline Leavitt, 27, was Trump's campaign press secretary and currently a spokesperson for his transition. She would be the youngest White House press secretary in history. The White House press secretary typically serves as the public face of the administration and historically has held daily briefings for the press corps. Leavitt, a New Hampshire native, was a spokesperson for MAGA Inc., a super PAC supporting Trump, before joining his 2024 campaign. In 2022, she ran for Congress in New Hampshire, winning a 10-way Republican primary before losing to Democratic Rep. Chris Pappas. Leavitt worked in the White House press office during Trump's first term before she became communications director for New York Republican Rep. Elise Stefanik, Trump's choice for U.S. ambassador to the United Nations. Former Hawaii Rep. Tulsi Gabbard has been tapped by Trump to be director of national intelligence, keeping with the trend to stock his Cabinet with loyal personalities rather than veteran professionals in their requisite fields. Gabbard, 43, was a Democratic House member who unsuccessfully sought the party's 2020 presidential nomination before leaving the party in 2022. She endorsed Trump in August and campaigned often with him this fall. “I know Tulsi will bring the fearless spirit that has defined her illustrious career to our Intelligence Community,” Trump said in a statement. Gabbard, who has served in the Army National Guard for more than two decades, deploying to Iraq and Kuwait, would come to the role as somewhat of an outsider compared to her predecessor. The current director, Avril Haines, was confirmed by the Senate in 2021 following several years in a number of top national security and intelligence positions. Trump has picked John Ratcliffe, a former Texas congressman who served as director of national intelligence during his first administration, to be director of the Central Intelligence Agency in his next. Ratcliffe was director of national intelligence during the final year and a half of Trump's first term, leading the U.S. government's spy agencies during the coronavirus pandemic. “I look forward to John being the first person ever to serve in both of our Nation's highest Intelligence positions,” Trump said in a statement, calling him a “fearless fighter for the Constitutional Rights of all Americans” who would ensure “the Highest Levels of National Security, and PEACE THROUGH STRENGTH.” Trump has chosen former New York Rep. Lee Zeldin to serve as his pick to lead the Environmental Protection Agency . Zeldin does not appear to have any experience in environmental issues, but is a longtime supporter of the former president. The 44-year-old former U.S. House member from New York wrote on X , “We will restore US energy dominance, revitalize our auto industry to bring back American jobs, and make the US the global leader of AI.” “We will do so while protecting access to clean air and water,” he added. During his campaign, Trump often attacked the Biden administration's promotion of electric vehicles, and incorrectly referring to a tax credit for EV purchases as a government mandate. Trump also often told his audiences during the campaign his administration would “Drill, baby, drill,” referring to his support for expanded petroleum exploration. In a statement, Trump said Zeldin “will ensure fair and swift deregulatory decisions that will be enacted in a way to unleash the power of American businesses, while at the same time maintaining the highest environmental standards, including the cleanest air and water on the planet.” Trump has named Brendan Carr, the senior Republican on the Federal Communications Commission, as the new chairman of the agency tasked with regulating broadcasting, telecommunications and broadband. Carr is a longtime member of the commission and served previously as the FCC’s general counsel. He has been unanimously confirmed by the Senate three times and was nominated by both Trump and President Joe Biden to the commission. Carr made past appearances on “Fox News Channel," including when he decried Democratic Vice President Kamala Harris' pre-Election Day appearance on “Saturday Night Live.” He wrote an op-ed last month defending a satellite company owned by Trump supporter Elon Musk. Rep. Elise Stefanik is a representative from New York and one of Trump's staunchest defenders going back to his first impeachment. Elected to the House in 2014, Stefanik was selected by her GOP House colleagues as House Republican Conference chair in 2021, when former Wyoming Rep. Liz Cheney was removed from the post after publicly criticizing Trump for falsely claiming he won the 2020 election. Stefanik, 40, has served in that role ever since as the third-ranking member of House leadership. Stefanik’s questioning of university presidents over antisemitism on their campuses helped lead to two of those presidents resigning, further raising her national profile. If confirmed, she would represent American interests at the U.N. as Trump vows to end the war waged by Russia against Ukraine begun in 2022. He has also called for peace as Israel continues its offensive against Hamas in Gaza and its invasion of Lebanon to target Hezbollah. President-elect Donald Trump says he's chosen former acting Attorney General Matt Whitaker to serve as U.S. ambassador to NATO. Trump has expressed skepticism about the Western military alliance for years. Trump said in a statement Wednesday that Whitaker is “a strong warrior and loyal Patriot” who “will ensure the United States’ interests are advanced and defended” and “strengthen relationships with our NATO Allies, and stand firm in the face of threats to Peace and Stability.” The choice of Whitaker as the nation’s representative to the North Atlantic Treaty Organization is an unusual one, given his background is as a lawyer and not in foreign policy. A Republican congressman from Michigan who served from 1993 to 2011, Hoekstra was ambassador to the Netherlands during Trump's first term. “In my Second Term, Pete will help me once again put AMERICA FIRST,” Trump said in a statement announcing his choice. “He did an outstanding job as United States Ambassador to the Netherlands during our first four years, and I am confident that he will continue to represent our Country well in this new role.” Trump will nominate former Arkansas Gov. Mike Huckabee to be ambassador to Israel. Huckabee is a staunch defender of Israel and his intended nomination comes as Trump has promised to align U.S. foreign policy more closely with Israel's interests as it wages wars against the Iran-backed Hamas and Hezbollah. “He loves Israel, and likewise the people of Israel love him,” Trump said in a statement. “Mike will work tirelessly to bring about peace in the Middle East.” Huckabee, who ran unsuccessfully for the Republican presidential nomination in 2008 and 2016, has been a popular figure among evangelical Christian conservatives, many of whom support Israel due to Old Testament writings that Jews are God’s chosen people and that Israel is their rightful homeland. Trump has been praised by some in this important Republican voting bloc for moving the U.S. embassy in Israel from Tel Aviv to Jerusalem. Trump on Tuesday named real estate investor Steven Witkoff to be special envoy to the Middle East. The 67-year-old Witkoff is the president-elect's golf partner and was golfing with him at Trump's club in West Palm Beach, Florida, on Sept. 15, when the former president was the target of a second attempted assassination. Witkoff “is a Highly Respected Leader in Business and Philanthropy,” Trump said of Witkoff in a statement. “Steve will be an unrelenting Voice for PEACE, and make us all proud." Trump also named Witkoff co-chair, with former Georgia Sen. Kelly Loeffler, of his inaugural committee. Trump said Wednesday that he will nominate Gen. Keith Kellogg to serve as assistant to the president and special envoy for Ukraine and Russia. Kellogg, a retired Army lieutenant general who has long been Trump’s top adviser on defense issues, served as National Security Advisor to Trump's former Vice President Mike Pence. For the America First Policy Institute, one of several groups formed after Trump left office to help lay the groundwork for the next Republican administration, Kellogg in April wrote that “bringing the Russia-Ukraine war to a close will require strong, America First leadership to deliver a peace deal and immediately end the hostilities between the two warring parties.” (AP Photo/Mariam Zuhaib) Trump asked Rep. Michael Waltz, R-Fla., a retired Army National Guard officer and war veteran, to be his national security adviser, Trump announced in a statement Tuesday. The move puts Waltz in the middle of national security crises, ranging from efforts to provide weapons to Ukraine and worries about the growing alliance between Russia and North Korea to the persistent attacks in the Middle East by Iran proxies and the push for a cease-fire between Israel and Hamas and Hezbollah. “Mike has been a strong champion of my America First Foreign Policy agenda,” Trump's statement said, "and will be a tremendous champion of our pursuit of Peace through Strength!” Waltz is a three-term GOP congressman from east-central Florida. He served multiple tours in Afghanistan and also worked in the Pentagon as a policy adviser when Donald Rumsfeld and Robert Gates were defense chiefs. He is considered hawkish on China, and called for a U.S. boycott of the 2022 Winter Olympics in Beijing due to its involvement in the origin of COVID-19 and its mistreatment of the minority Muslim Uighur population. Stephen Miller, an immigration hardliner , was a vocal spokesperson during the presidential campaign for Trump's priority of mass deportations. The 39-year-old was a senior adviser during Trump's first administration. Miller has been a central figure in some of Trump's policy decisions, notably his move to separate thousands of immigrant families. Trump argued throughout the campaign that the nation's economic, national security and social priorities could be met by deporting people who are in the United States illegally. Since Trump left office in 2021, Miller has served as the president of America First Legal, an organization made up of former Trump advisers aimed at challenging the Biden administration, media companies, universities and others over issues such as free speech and national security. Thomas Homan, 62, has been tasked with Trump’s top priority of carrying out the largest deportation operation in the nation’s history. Homan, who served under Trump in his first administration leading U.S. Immigration and Customs Enforcement, was widely expected to be offered a position related to the border, an issue Trump made central to his campaign. Though Homan has insisted such a massive undertaking would be humane, he has long been a loyal supporter of Trump's policy proposals, suggesting at a July conference in Washington that he would be willing to "run the biggest deportation operation this country’s ever seen.” Democrats have criticized Homan for his defending Trump's “zero tolerance” policy on border crossings during his first administration, which led to the separation of thousands of parents and children seeking asylum at the border. Dr. Mehmet Oz, 64, is a former heart surgeon who hosted “The Dr. Oz Show,” a long-running daytime television talk show. He ran unsuccessfully for the U.S. Senate as the Republican nominee in 2022 and is an outspoken supporter of Trump, who endorsed Oz's bid for elected office. Elon Musk, left, and Vivek Ramaswamy speak before Republican presidential nominee former President Donald Trump at an Oct. 27 campaign rally at Madison Square Garden in New York. Trump on Tuesday said Musk and former Republican presidential candidate Ramaswamy will lead a new “Department of Government Efficiency" — which is not, despite the name, a government agency. The acronym “DOGE” is a nod to Musk's favorite cryptocurrency, dogecoin. Trump said Musk and Ramaswamy will work from outside the government to offer the White House “advice and guidance” and will partner with the Office of Management and Budget to “drive large scale structural reform, and create an entrepreneurial approach to Government never seen before.” He added the move would shock government systems. It's not clear how the organization will operate. Musk, owner of X and CEO of Tesla and SpaceX, has been a constant presence at Mar-a-Lago since Trump won the presidential election. Ramaswamy suspended his campaign in January and threw his support behind Trump. Trump said the two will “pave the way for my Administration to dismantle Government Bureaucracy, slash excess regulations, cut wasteful expenditures, and restructure Federal Agencies.” Russell Vought held the position during Trump’s first presidency. After Trump’s initial term ended, Vought founded the Center for Renewing America, a think tank that describes its mission as “renew a consensus of America as a nation under God.” Vought was closely involved with Project 2025, a conservative blueprint for Trump’s second term that he tried to distance himself from during the campaign. Vought has also previously worked as the executive and budget director for the Republican Study Committee, a caucus for conservative House Republicans. He also worked at Heritage Action, the political group tied to The Heritage Foundation, a conservative think tank. Dan Scavino, deputy chief of staff Scavino, whom Trump's transition referred to in a statement as one of “Trump's longest serving and most trusted aides,” was a senior adviser to Trump's 2024 campaign, as well as his 2016 and 2020 campaigns. He will be deputy chief of staff and assistant to the president. Scavino had run Trump's social media profile in the White House during his first administration. He was also held in contempt of Congress in 2022 after a month-long refusal to comply with a subpoena from the House committee’s investigation into the Jan. 6, 2021, attack on the U.S. Capitol. James Blair, deputy chief of staff Blair was political director for Trump's 2024 campaign and for the Republican National Committee. He will be deputy chief of staff for legislative, political and public affairs and assistant to the president. Blair was key to Trump's economic messaging during his winning White House comeback campaign this year, a driving force behind the candidate's “Trump can fix it” slogan and his query to audiences this fall if they were better off than four years ago. Taylor Budowich, deputy chief of staff Budowich is a veteran Trump campaign aide who launched and directed Make America Great Again, Inc., a super PAC that supported Trump's 2024 campaign. He will be deputy chief of staff for communications and personnel and assistant to the president. Budowich also had served as a spokesman for Trump after his presidency. William McGinley, White House counsel McGinley was White House Cabinet secretary during Trump's first administration, and was outside legal counsel for the Republican National Committee's election integrity effort during the 2024 campaign. In a statement, Trump called McGinley “a smart and tenacious lawyer who will help me advance our America First agenda, while fighting for election integrity and against the weaponization of law enforcement.” Jay Bhattacharya, National Institutes of Health Trump has chosen Dr. Jay Bhattacharya to lead the National Institutes of Health. Bhattacharya is a physician and professor at Stanford University School of Medicine, and is a critic of pandemic lockdowns and vaccine mandates. He promoted the idea of herd immunity during the pandemic, arguing that people at low risk should live normally while building up immunity to COVID-19 through infection. The National Institutes of Health funds medical research through competitive grants to researchers at institutions throughout the nation. NIH also conducts its own research with thousands of scientists working at its labs in Bethesda, Maryland. Jamieson Greer, U.S. trade representative Kevin Hassett, Director of the White House National Economic Council Trump is turning to two officials with experience navigating not only Washington but the key issues of income taxes and tariffs as he fills out his economic team. He announced he has chosen international trade attorney Jamieson Greer to be his U.S. trade representative and Kevin Hassett as director of the White House National Economic Council. While Trump has in several cases nominated outsiders to key posts, these picks reflect a recognition that his reputation will likely hinge on restoring the public’s confidence in the economy. Trump said in a statement that Greer was instrumental in his first term in imposing tariffs on China and others and replacing the trade agreement with Canada and Mexico, “therefore making it much better for American Workers.” Hassett, 62, served in the first Trump term as chairman of the Council of Economic Advisers. He has a doctorate from the University of Pennsylvania and worked at the right-leaning American Enterprise Institute before joining the Trump White House in 2017. Get Government & Politics updates in your inbox! Stay up-to-date on the latest in local and national government and political topics with our newsletter.
Go for medal, Yasawa athletes urgedNEW YORK (AP) — A number of President-elect Donald Trump 's most prominent Cabinet picks and appointees have been targeted by bomb threats and “swatting attacks," Trump's transition team said Wednesday. The FBI said it was investigating. “Last night and this morning, several of President Trump’s Cabinet nominees and Administration appointees were targeted in violent, unAmerican threats to their lives and those who live with them," Trump transition spokesperson Karoline Leavitt said in a statement. The attacks ranged from bomb threats to swatting, in which attackers initiate an emergency law enforcement response against a target victim under false pretenses, she said. The tactic has become a popular one in recent years. Leavitt said law enforcement and other authorities acted quickly to ensure the safety of those who were targeted and Trump and his transition team are grateful. Among those targeted were New York Rep. Elise Stefanik, Trump’s pick to serve as the next ambassador to the United Nations ; Matt Gaetz, Trump’s initial pick to serve as attorney general ; Oregon Rep. Lori Chavez-DeRemer, whom Trump chose to lead the Department of Labor , and former New York congressman Lee Zeldin, who has been tapped to lead the Environmental Protection Agency. Law enforcement officials are also looking into whether Susie Wiles, Trump’s incoming chief of staff, and Pam Bondi, the former Florida attorney general whom Trump has chosen as Gaetz’s replacement, and other incoming administration officials were also victims — as well as how each was targeted, according to a law enforcement official who spoke on condition of anonymity as the investigation continues. Wiles and Bondi did not immediately respond to requests for comment. The FBI said in a statement that it was “aware of numerous bomb threats and swatting incidents targeting incoming administration nominees and appointees" and was investigating with its law enforcement partners. White House spokesperson Saloni Sharma said President Joe Biden had been briefed and the White House is in touch with federal law enforcement and Trump's transition team. Biden “continues to monitor the situation closely," Sharma said, adding the president and his administration “condemn threats of political violence.” Stefanik's office said that, on Wednesday morning, she, her husband, and their 3-year-old son were driving home from Washington for Thanksgiving when they were informed of a bomb threat to their residence in Saratoga County. Police swept Stefanik’s home on Wednesday morning in response to the bomb threat but did not locate any explosive devices, New York State Police said. Zeldin said in a social media post that he and his family had also been threatened. “A pipe bomb threat targeting me and my family at our home today was sent in with a pro-Palestinian themed message,” he wrote on X . “My family and I were not home at the time and are safe." In Florida, the Okaloosa County sheriff’s office said on Facebook that it “received notification of a bomb threat referencing former Congressman Matt Gaetz’s supposed mailbox at a home in the Niceville area" Wednesday. While a family member resides at the address, the office said, Gaetz “is NOT a resident.” No threatening devices were found. Story continues below video Gaetz was Trump’s initial pick to serve as attorney general, but he withdrew from consideration after allegations that he paid women for sex and slept with underage women. Gaetz has vehemently denied any wrongdoing, and a Justice Department investigation into sex trafficking allegations ended with no charges against him. The threats follow a political campaign marked by disturbing and unprecedented violence. In July, a gunman opened fire at a Trump rally in Butler, Pennsylvania, grazing the then-candidate in the ear with a bullet and killing one of his supporters. The Secret Service later thwarted a subsequent assassination attempt at Trump's West Palm Beach, Florida, golf course when an agent spotted the barrel of a gun poking through a perimeter fence while Trump was golfing. Trump was also the subject of an Iranian murder-for-hire plot , with a man saying he had been tasked with planning the assassination of the Republican president-elect. Also this week, authorities arrested a man they say posted videos on social media threatening to kill Trump, according to court documents. In one video posted on Nov. 13, Manuel Tamayo-Torres threatened to shoot the former president while holding what appeared to be an AR-15 style rifle, authorities said Among the other videos he posted was one from an arena in Glendale, Arizona on Aug. 23, the same day Trump held a campaign rally there, according to court papers. An attorney for Tamayo-Torres did not immediately respond to a request for comment Wednesday. Public figures across the political spectrum have been targeted in recent years by hoax bomb threats and false reports of shootings at their homes. About a year ago the FBI responded to an uptick in such incidents at the homes of public officials, state capitols and courthouses across the country around the holidays. Many were locked down and evacuated in early January after receiving bomb threats. No explosives were found and no one was hurt. Some of those targeted last year were Georgia Lt. Gov. Burt Jones, Boston Mayor Michelle Wu and Ohio Attorney General Dave Yost. The judges overseeing the civil fraud case against Trump in New York and the criminal election interference case against him in Washington were both targeted earlier this year. Justice Department special counsel Jack Smith, who recently abandoned the two criminal cases he brought against Trump, was also the subject of a fake emergency call on Christmas Day last year. Earlier this year, schools, government buildings and the homes of city officials in Springfield, Ohio, received a string of hoax bomb threats after Trump falsely accused members of Springfield’s Haitian community of abducting and eating cats and dogs. And in 2022, a slew of historically Black colleges and universities nationwide were targeted with dozens of bomb threats, with the vast majority arriving during the celebration of Black History Month. The U.S. Capitol Police said in a statement Wednesday that anytime a member of Congress is the victim of a swatting' incident, “we work closely with our local and federal law enforcement partners.” The force declined to provide further details, in part to “minimize the risk of copy-cats.” Republican House Speaker Mike Johnson called the threats “dangerous and unhinged.” “This year, there was not just one but TWO assassination attempts on President Trump," he wrote on X . “Now some of his Cabinet nominees and their families are facing bomb threats.” He added: “It is not who we are in America.” ___ Richer reported from Washington. Associated Press writers Colleen Long and Eric Tucker in Washington, Scott Bauer in Madison, Wisconsin, and Anthony Izaguirre in Albany, New York, contributed to this report.KMDK leader stresses urgent implementation of Pandiyar-Punnampuzha scheme
BIRMINGHAM, Ala. (AP) — Noah Feddersen had 17 points in North Dakota State's 73-61 victory against West Georgia on Wednesday night. Feddersen added nine rebounds for the Bison (4-4). Masen Miller added 15 points while finishing 5 of 9 from 3-point range while he also had six rebounds. Brennan Watkins had 14 points and shot 4 for 5 (3 for 4 from 3-point range) and 3 of 3 from the free-throw line. The Wolves (0-8) were led by Shelton Williams-Dryden, who posted 19 points, eight rebounds and two steals. Tauris Watson added 14 points for West Georgia. ___ The Associated Press created this story using technology provided by and data from . The Associated Press